Mrsać is a village situated in Kraljevo municipality in Serbia.
Coordinates: 43°45′N 20°34′E / 43.750°N 20.567°E / 43.750; 20.567
Methicillin-resistant Staphylococcus aureus (MRSA) (/ɛmɑːrɛseɪ/ or /ˈmɜːrsə/) is a bacterium responsible for several difficult-to-treat infections in humans. It is also called oxacillin-resistant Staphylococcus aureus (ORSA). MRSA is any strain of Staphylococcus aureus that has developed, through the process of natural selection, resistance to beta-lactam antibiotics, which include the penicillins (methicillin, dicloxacillin, nafcillin, oxacillin, etc.) and the cephalosporins. Strains unable to resist these antibiotics are classified as methicillin-sensitive Staphylococcus aureus, or MSSA. The evolution of such resistance does not cause the organism to be more intrinsically virulent than strains of S. aureus that have no antibiotic resistance, but resistance does make MRSA infection more difficult to treat with standard types of antibiotics and thus more dangerous.
MRSA is especially troublesome in hospitals, prisons, and nursing homes, where patients with open wounds, invasive devices, and weakened immune systems are at greater risk of nosocomial infection than the general public. MRSA began as a hospital-acquired infection, but has developed limited endemic status and is now sometimes community-acquired and livestock-acquired. The terms HA-MRSA (healthcare-associated MRSA), CA-MRSA (community-associated MRSA) and LA-MRSA (livestock-associated) reflect this distinction.
2-Ketoarginine methyltransferase (EC 2.1.1.243, mrsA (gene)) is an enzyme with system name S-adenosyl-L-methionine:5-carbamimidamido-2-oxopentanoate S-methyltransferase. This enzyme catalyses the following chemical reaction
The enzyme is involved in production of the rare amino acid 3-methylarginine.
Bonkers may refer to:
Bonkers! was an ATV variety show, distributed by ITC Entertainment in the United States for syndication during the 1978-79 television season, and later airing in 1979 in the United Kingdom. Made at ATV's Elstree studios near London.
Starring Bob Monkhouse and the Hudson Brothers - Bill, Brett and Mark - the show featured sketches, guest stars and musical numbers from the chorus dancers known as The Bonkerettes. Whilst not a big hit for ATV, it gained a cult audience in the United States where it was compared to Saturday Night Live.
After four episodes the show was curtailed in the UK by the 13-week-long ITV strike of 1979 and did not reappear when the network restarted broadcasts; however, production for syndication continued and 24 episodes in total were made.
Bonkers! (also known as This Game is Bonkers!) was a race-style board game designed by Paul J. Gruen and produced by Parker Brothers and later by Milton Bradley. The object was to be the first player to score 12 points by adding instruction cards to the empty spaces in an attempt to move to several scoring stations. The game's slogan (for both versions) was "It's Never the Same Game Twice!"
Each game of Bonkers! came with the following: