A drug is any substance other than food, that when inhaled, injected, smoked, consumed, absorbed via a patch on the skin or dissolved under the tongue causes a physiological change in the body.
In pharmacology, a pharmaceutical drug or medicine, is a chemical substance used to treat, cure, prevent, diagnose a disease or promote well-being. Traditionally drugs were obtained through extraction from medicinal plants, but more recently also by organic synthesis. Pharmaceutical drugs may be used for a limited duration, or on a regular basis for chronic disorders.
Pharmaceutical drugs are often classified into drug classes—groups of related drugs that have similar chemical structures, the same mechanism of action (binding to the same biological target), a related mode of action, and that are used to treat the same disease. The Anatomical Therapeutic Chemical Classification System (ATC), the most widely used drug classification system, assigns drugs a unique ATC code, which is an alphanumeric code that assigns it to specific drug classes within the ATC system. Another major classification system is the Biopharmaceutics Classification System. This classifies drugs according to their solubility and permeability or absorption properties.
Shithead (also known as Karma, Palace, Shed, Three Card Game and by many other names) is a card game similar to the Finnish game Paskahousu. In the game the object is to lose all of one's cards, with the last player to do so being the "shithead", who must deal the next game and may be subject to some minor forfeit of the group's choice, such as fetching the next round of drinks.
The game, and variations of it, is popular in many countries amongst backpackers, and as a result is widespread. Although the basic structure of the game generally remains constant there are often regional variations of the game's original rules.
There are many variations of the rules, and there is no universally accepted set. A common set of rules is listed here.
From a standard, shuffled deck of 52 cards, each player is dealt three face-down cards in a row. Players are not allowed to see or change these cards. On top of the face-down cards, they are dealt the same number of face-up cards. Three cards are again dealt to each player (face down), and this becomes the player's hand.
Drugs is a peer-reviewed medical journal published by Adis International (Springer Science + Business Media) that covers topics in drugs and therapeutics. Besides research articles, the journal also publishes "Adis Drug Evaluations and Profiles", evidence-based, single-agent reviews.
Drugs is abstracted and indexed in:
According to the Journal Citation Reports it received an impact factor of 4.343, ranking it 9th out of 87 journals in the category "Toxicology" and ranking it 32nd out of 254 journals in the category "Pharmacology & Pharmacy"
Bizarre may refer to:
Bizarre are a rock band from Blanes, Catalonia, Spain. They are best known in their country by their 2006 hit single "Sé", which is widely played not only in Catalonia and Spain but also in some Latin American countries.
Although their songs are mostly sung in Spanish, several of them have been also recorded in Catalan ("Sé", "Difícil d'oblidar", "No és massa tard", "T'amagues"...), English ("Alone in NY" and some unreleased demos) and Italian ("So").
Bizarre have released up to date two albums: their debut Bizarre (Mass Records, 2006) and Zero (Mass Records, 2010).
Bizarre is a Canadian sketch comedy television series that aired from 1980 to 1986. The show was hosted by John Byner, and produced by CTV at the CFTO Glen-Warren Studios in suburban Toronto for first-run airing in Canada on CTV and in the United States on the Showtime premium cable network.
The series featured slapstick sketches, monologues, TV parodies, and performances by guest stand-up comics. Byner's interactions with members of the studio audience, or with show producer Bob Einstein (who often came in to halt a sketch midway through), provided an early example of removing the fourth wall. Much of the humour on the show was considered risque during the original run of the series.
The series utilized a rotating ensemble of supporting actors who backed Byner up in his sketches. Besides Einstein, this group included Philip Akin, Harvey Atkin, Cynthia Belliveau, Jack Duffy, Jayne Eastwood, Barbara Hamilton, John Hemphill, Barry Flatman, Keith Knight, Don Lake, Kathleen Laskey, Kate Lynch, Pat Morita, Debra McGrath, Mike Myers, Melissa Steinberg, Billy Van, Billy Barty, Steve Weston, and Wayne and Shuster alumnus Tom Harvey.