Bifonazole

Bifonazole is an imidazole antifungal drug. Bifonazole is marketed by Bayer under the trade mark Canespor in ointment form.

Mechanism of action

Bifonazole has dual mode of action. It blocks transformation of 24-methylendihydrolanosterol to desmethylsterol in fungi together with inhibition of HMG-CoA. This enables fungicidal properties against dermatophytes and distinguishes bifonazole from other antifungal drugs.

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