Blessthefall

Blessthefall (stylized as blessthefall) is an American metalcore band from Phoenix, Arizona, signed to Fearless Records. The band was founded in 2003 by guitarist Mike Frisby, drummer Matt Traynor, and bassist Jared Warth. Their debut album, His Last Walk, with original vocalist Craig Mabbitt, was released April 10, 2007. Their second studio album, Witness, with current vocalist Beau Bokan, was released October 6, 2009. Their third studio album, Awakening, was released on October 4, 2011. Their fourth studio album, Hollow Bodies, was released on August 20, 2013. To Those Left Behind is the band's fifth full-length album, released on September 18, 2015.

History

Origins and His Last Walk (2003–2007)

Blessthefall grew out of high school practice sessions consisting of rhythm guitarists Mike Frisby and Eric Lambert, lead guitarist Miles Bergsma, drummer Matt Traynor, bassist and vocalist Jared Warth, and later, vocalist Craig Mabbitt and keyboardist Andrew Barr. After founding member Miles Bergsma left to attend college at the Berklee College of Music in Boston, they released a three-track EP and rhythm guitarist Eric Lambert move to lead guitar to form their first solid line-up. Phoenix-area gigs with Greeley Estates and an openly religious orientation got the band local press and a deal with Warner subsidiary, Science Records. The band then toured with Alesana and Norma Jean across the United States and Canada. Their debut album, His Last Walk, was released on April 10, 2007, to mixed reviews.His Last Walk peaked at No. 32 on the U.S. Billboard Heatseekers chart. Their debut album sold over 65,000 copies and its singles sold over 100,000 copies.

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This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/Blessthefall

BTF3

Transcription factor BTF3 is a protein that in humans is encoded by the BTF3 gene.

Function

This gene encodes the basic transcription factor 3. This protein forms a stable complex with RNA polymerase IIB and is required for transcriptional initiation. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene has multiple pseudogenes.

Interactions

BTF3 has been shown to interact with CSNK2B.

References

Further reading


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This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/BTF3

XPB

XPB (xeroderma pigmentosum type B) is an ATP-dependent DNA helicase in humans that is a part of the TFIIH transcription factor complex.

Structure

The 3D-structure of the archaeal homolog of XPB has been solved by X-ray crystallography by Dr. John Tainer and his group at The Scripps Research Institute.

Function

XPB plays a significant role in normal basal transcription, transcription coupled repair (TCR), and nucleotide excision repair (NER). Purified XPB has been shown to unwind DNA with 3’-5’ polarity.

Disorders

Mutations in XPB and other related complementation groups, XPA-XPG, leads to a number of genetic disorders such as Xeroderma pigmentosum, Cockayne's syndrome, and trichothiodystrophy.

Interactions

XPB has been shown to interact with:

  • BCR gene,
  • CDK7,
  • ERCC2,
  • GTF2H1,
  • GTF2H2,
  • GTF2H4,
  • GTF2H5,
  • P53,
  • PSMC5, and
  • XPC.

    • See also

  • XP

    • References

    Further reading

    External links

  • GeneReviews/NIH/NCBI/UW entry on Xeroderma Pigmentosum
  • XPBC-ERCC-3 protein at the US National Library of Medicine Medical Subject Headings (MeSH)
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    This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/XPB

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