BRCT domain
BRCA1 C Terminus (BRCT) domain is a family of evolutionarily related proteins.
The BRCT domain (after the C_terminal domain of a breast cancer susceptibility protein) is found predominantly in proteins involved in cell cycle checkpoint functions responsive to DNA damage, for example as found in the breast cancer DNA-repair protein BRCA1. The domain is an approximately 100 amino acid tandem repeat, which appears to act as a phospho-protein binding domain.
Examples
Human proteins containing this domain include:
References
External links
This article incorporates text from the public domain Pfam and InterPro IPR001357
Podcasts:
Breakout
by: DemonYou know they're after us
Do you know how far we are?
Breakout
The dog are closing in
Soon we'll reach the breakers yard
Head for the underground
Leave all the creatures to play
No-one ever goes there anymore
The rats on holiday
We can stay for a short while here
You're on of the privileged few
When it's over make up your own mind
What you wanna do
Now we're breaking with the past
Living dangerously once more
We're going across the line
Breakout
You know they're after us
Do you know how far we are?
Breakout
The dog are closing in
Soon we'll reach the breakers yard
Don't look back
There's nothing but
Builders dreams in sinking sand
Don't make waves for someone else
It's not the time to make a stand
See the lights in the distance
Gleaming pillars of steal
It's time to take off the new disguise
There's nothing left to fear
They'll be hiding till the battle dies down
There's so much depending on you
We dare not make a mistake at this level
We all have to get through
Now we're breaking with the past
Living dangerously once more
We're going across the line
Breakout
You know they're after us
Do you know how far we are?
Breakout
The dog are closing in
Soon we'll reach the breakers yard
Don't look back
There's nothing but
Builders dreams in sinking sand
Don't make waves for someone else