BRCA2 and BRCA2 (/ˌbrækəˈtuː/) are a human gene and its protein product, respectively. The official symbol (BRCA2, italic for the gene, nonitalic for the protein) and the official name (breast cancer 2) are maintained by the HGNC. Orthologs, styled Brca2 and Brca2, are common in other mammal species.BRCA2 is a human tumor suppressor gene (specifically, a caretaker gene), found in all humans; its protein, also called by the synonym breast cancer type 2 susceptibility protein, is responsible for repairing DNA.
BRCA2 and BRCA1 are normally expressed in the cells of breast and other tissue, where they help repair damaged DNA or destroy cells if DNA cannot be repaired. They are involved in the repair of chromosomal damage with an important role in the error-free repair of DNA double strand breaks. If BRCA1 or BRCA2 itself is damaged by a BRCA mutation, damaged DNA is not repaired properly, and this increases the risk for breast cancer. Thus, although the terms "breast cancer susceptibility gene" and "breast cancer susceptibility protein" (used frequently both in and outside the medical literature) sound as if they describe a proto-oncogene or oncogene, BRCA1 and BRCA2 are "normal"; it is their mutation that is abnormal.
More nightmares
Someone wake me when they're through
Stop my lover's ghost from trying to protrude
(You're burning, you're burning)
It's chaotic, but I've got it
You're letter scratched across my throat
Like some painter's ink, spilled the canvas soiling parts of me
Cover up, cover up, all the fusion's lost
I know this sucks but one day you'll meet up
I miss the softness of your sound
The taste of you left in my mouth
Is Mississippi done yet burning?
Sick sounds like stomach's stinging
I search out, but you cannot be found
A red horizon in the south
Is Mississippi done yet burning?
Most nights bleat every feeling
I must get back to you somehow
I must get back to you
Your shadow
Now lies against the moon
The skin I touched that once
Kissed has come unglued
(You're burning, you're burning)
It's chaotic, but I've got it
More screams than anyone should hear
The voice of you stabs in my chest
Forged and faithless
Cover up, cover up, all the fusion's lost
I know this sucks but one day you'll meet up
I miss the softness of your sound
The taste of you left in my mouth
Is Mississippi done yet burning?
Sick sounds like stomach's stinging
I search out, but you cannot be found
A red horizon in the south
Is Mississippi done yet burning?
Most nights bleat every feeling
I must get back to you somehow
I must get back to you
Darling boy
Lift your chin up for me now
For my face to see
And I am smiling looking down
I know you're out of breath
You're hit by the way I've left
Just hold me tried and true
For I'll be waiting
Waiting here for you
So dim these lights, I won't be found
This haunting stops right here and now
There's pain and in his eyes of fixed dreaming
I'm tired without you, so let it be
So dim these lights, I won't be found
This haunting stops right here and now
There's pain in his eyes of fixed dreaming
I'm tired without you, so let it be
Is Mississippi done yet burning?
Most nights bleat every feeling
I must get back to you somehow