Biogen is an American global biotechnology company based in Cambridge, Massachusetts, specializing in the discovery, development, and delivery of therapies for the treatment of neurodegenerative, hematologic, and autoimmune diseases to patients worldwide.
Biogen was founded in 1978 in Geneva by several prominent biologists, including Kenneth Murray of the University of Edinburgh, Phillip Allen Sharp of the Massachusetts Institute of Technology, Walter Gilbert of Harvard (who served as CEO during the start-up phase) and Charles Weissmann, University of Zurich (who contributed the first product interferon alpha). Gilbert and Sharp were subsequently honored with Nobel Prizes: Gilbert was recognized in 1980 with the Nobel Prize in Chemistry for his work in understanding DNA sequencing, while Sharp received the Nobel Prize in Physiology or Medicine in 1993 for his discovery of split genes.
In 2003, Biogen merged with San Diego, California-based IDEC Pharmaceuticals (formed in 1986 by biotech pioneers Ivor Royston and Howard Birndorf) and adopted the name Biogen Idec. After the merge, Biogen Idec became the 3rd largest Biotechnology company in the world. Following shifts in research core areas, the company has since shortened its name, reverting to simply Biogen.
A stock exchange or bourse is an exchange where stock brokers and traders can buy and/or sell stocks (also called shares), bonds, and other securities. Stock exchanges may also provide facilities for issue and redemption of securities and other financial instruments, and capital events including the payment of income and dividends. Securities traded on a stock exchange include stock issued by listed companies, unit trusts, derivatives, pooled investment products and bonds. Stock exchanges often function as "continuous auction" markets, with buyers and sellers consummating transactions at a central location, such as the floor of the exchange.
To be able to trade a security on a certain stock exchange, it must be listed there. Usually, there is a central location at least for record keeping, but trade is increasingly less linked to such a physical place, as modern markets use electronic networks, which gives them advantages of increased speed and reduced cost of transactions. Trade on an exchange is restricted to brokers who are members of the exchange. In recent years, various other trading venues, such as electronic communication networks, alternative trading systems and "dark pools" have taken much of the trading activity away from traditional stock exchanges.
BIIB033 (also known as Anti-LINGO-1) is a monoclonal antibody targeting LINGO1. It is currently being developed by Biogen as a treatment for diseases such as multiple sclerosis and optic neuritis.
Wer sht dann, dat ich dich noch vermess un
Ich hing nur noch vr der Kess?Nchtelang, dat ess wirklich nit wohr.
N, em hnz, ich saach et dir, hhr mir joot zo:
Aff un zo sinn andre Fraue do, aff un zo.
Jo, ich kumme schon kloor.
Joot, ich drink jetz'e paar Droppe mieh,
Doch, wat soll't et deit ech nit mieh wieh.
Hann die janze Buud renoviert, woot och Zigg un ich saach et dir:
Htt sich rentiert, he ess nix mieh, wat zo dunn htt met dir, nur om
Flur dat verstemmte Klavier.
Ahnunfrsich denk ich kaum noch ahn dich,
Jarkei Problem ich hann alles om Schirm.
Ahnunfrsich denk ich kauf noch ahn dich,
Ahnunfrsich.
Joot, ich hann lnger nit opjerhmp
Un dat Leejut knnt och weg, stemmp.
Vver nit, dat mer he nix mieh fingk,
Fing och nit, dat die Sphlmaschin
Noh Mllmmer stink
Un d Lou Reed noh Beerdijung klingk.
Wat wei ich, wovun d'm Augebleck singk!?
Nobby sht, et jv ene Typ,
Wo mer dich neuerdings off met sieht.
Denk jetz nit, dat mir dat ir'ndjet mht.
Jedenfalls, wenn d lppsch weed, roof ahn, saach
Mer Bescheid. Ich kumm jhn ens koot me'm Hammer vorbei un bring ihm