BBX (gene)

HMG box transcription factor BBX also known as bobby sox homolog or HMG box-containing protein 2 is a protein that in humans is encoded by the BBX gene.

Model organisms

Model organisms have been used in the study of BBX function. A conditional knockout mouse line, called Bbx^{tm1a(EUCOMM)Wtsi} was generated as part of the International Knockout Mouse Consortium program, a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists.

Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Twenty six tests were carried out on homozygous mutant adult mice and four significant abnormalities were observed. A study of body composition found decreases in bone mineral density and content, and a reduction in body length in female mice, while mutants of both sexes showed a reduction in lean body mass. Radiography found that males had abnormal teeth morphology. Females had a decreased heart weight, and both sexes had reduced IgA levels in their plasma.

Gene

A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.

Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term "having a gene" (e.g., "good genes," "hair colour gene") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.

Eugene (given name)

Eugene is a common (masculine) first name that comes from the Greek εὐγενής (eugenēs), "noble", literally "well-born", from εὖ (eu), "well" and γένος (genos), "race, stock, kin".Gene is a common shortened form. The feminine variant is Eugenia or Eugénie.

Male foreign-language variants include:

Notable people

Christianity

Military

Gene (novel)

Gene is a thriller novel by Stel Pavlou (born 1970), published in 2005 in England by Simon & Schuster. It is published in several languages with some title changes. The Italian edition has the title La Conspirazione del Minotauro (The Minotaur Conspiracy). The novel is about a fictional New York detective, James North, who in the process of hunting down a criminal, uncovers a genetics experiment to unlock past lives through genetic memory, therefore achieving a kind of immortality. In so doing North discovers his own origins, that of a soldier from the Trojan War who is reincarnated seven times through history, forced to confront his nemesis each time, all for the loss of his one true love.

Characters

Cyclades (born circa 1300 BC)

Incarnations of Cyclades

Athanatos (born circa 1500 BC)

Incarnations of Athanatos

BBX

BBX may refer to

See also

BBx

BBx is the original name for the "Business Basic eXtended" interpreter developed by BASIS International in 1985. Subsequent generations of BBx have been BBxPROGRESSION/2, BBxPROGRESSION/3, PROGRESSION/4, PRO/5, Visual PRO/5, and BBj. BASIS estimates that over 1.7 million end users worldwide run applications built with their products.

BBx dialects include PRO/5 (a character mode interpreter for Linux and Unix environments), Visual PRO/5 (a graphical interpreter for the Microsoft Windows environment), PRO/5 Data Server (a data server for PRO/5 data files), the BASIS ODBC Driver (a Microsoft Windows ODBC driver for PRO/5 data files).

The current generation of BBx - BBj - is a superset of the BBx language and environment implemented in Java.

References

External links

BlackBerry 10

BlackBerry 10 is a proprietary mobile operating system for the BlackBerry line of smartphones, both developed by BlackBerry Limited (formerly Research In Motion). BlackBerry 10 is based on QNX, a Unix-like operating system that was originally developed by QNX Software Systems until the company was acquired by BlackBerry in April 2010. As a result of the acquisition, BlackBerry released BlackBerry Tablet OS for the BlackBerry PlayBook, large parts of which were subsumed by BlackBerry 10.

It supports the application framework Qt (version 4.8) and features an Android runtime to run Android applications. Prior to version 10.3.1, BlackBerry 10 also supported the Adobe AIR runtime. The user interface uses a combination of gestures and touch-based interactions for navigation and control, making it possible to control a device without having to press any physical buttons, with the exception of the power button that switches the device on or off. It also supports hardware keyboards, including ones which support touch input.