BAZ1B
Tyrosine-protein kinase BAZ1B is an enzyme that in humans is encoded by the BAZ1B gene.
Function
This gene encodes a member of the bromodomain protein family. The bromodomain is a structural motif characteristic of proteins involved in chromatin-dependent regulation of transcription. This gene is deleted in Williams-Beuren syndrome, a developmental disorder caused by deletion of multiple genes at 7q11.23.
Animal models
Model organisms have been used in the study of BAZ1B function. A conditional knockout mouse line, called Baz1btm2a(KOMP)Wtsi, was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists — at the Wellcome Trust Sanger Institute.
Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion.
Six significant phenotypes were reported:
Podcasts:
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by George Jones
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by Insane Clown Posse
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by ICP (Insane Clown Posse)
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by Peggy Lee
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by I.C.P.
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by Boyz II Men
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by South Park Mexican
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by Pink Cream 69
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by Keri Hilson
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by Craig David
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by Slick Shoes
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by Pete Yorn
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by Ducky Boys
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by Skankin' Pickle
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by Big Country
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by Esham
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by Tonex
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by Spm
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by Rigby
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by B.t. Express
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by Cry Of Love
Pass Me By
by: George JonesWould you look at what came down the road today
Wanting me to be one more mistake to make
A bridge to burn to get to someone new
Hey, pass me by if you're only passing through.
You sure look like the traveling kind to me
Don't stop if this ain't where you want to be
I don't know what you think you run into
Hey pass me by if you're only passing through.
--- Instrumental ---
I'm not gonna be another stepping stone
Among the other hearts that you've walked on
Lord, help me if I fall in love with you
Hey, pass me by if you're only passing through.
You sure look like the traveling kind to me
Don't stop if this ain't where you want to be
I don't know what you think you run into
Hey, pass me by if you're only passing through.