Transcription regulator protein BACH2 is a protein that in humans is encoded by the BACH2 gene. It contains a BTB/POZ domain at its N-terminus which forms a disulphide-linked dimer and a bZip_Maf domain at the C-terminus.
Model organisms have been used in the study of BACH2 function. A conditional knockout mouse line called Bach2tm1a(EUCOMM)Wtsi was generated at the Wellcome Trust Sanger Institute. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping - in-depth bone and cartilage phenotyping
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
Sometimes I feel so lost S.O.S. all my lines are crossed. I bite off more than I can chew. It's killing me its killing you there's nothing that I'd rather do. It's got me now its holding me. A sign of something good a sign I thought I'd never see. I try to keep it in my head. We'll you can kick my ass and burn your books, but it won't change a word I've said. I guess I should have seen it coming. It's in the smile on his face. Did you really think that this would be so easy? I think you made a big mistake. What went so wrong? Every action has reaction in this fucked up world that you created. Now you're head is so full of negativity and shattered dreams. A world of noise you end up hating. It's got me now it's holding me. A sign of something good a sign I thought I'd never see. I try to keep it in my head. We'll you can kick my ass and burn you're books but it won't change a word I've said. I guess I should have seen it coming. It's in the smile on his face. Did you really think that this would be so easy? I think you made a big mistake. What went so wrong it's been too long. So just take it on the chin. It's who you are and what you do. Not who you were or what you have been. There's just one thing you should know. That I still care to work it out don't think about it let it go.