Ataxia

Ataxia (from Greek α- [a negative prefix] + -τάξις [order] = "lack of order") is a neurological sign consisting of lack of voluntary coordination of muscle movements that includes gait abnormality. Ataxia is a non-specific clinical manifestation implying dysfunction of the parts of the nervous system that coordinate movement, such as the cerebellum. Ataxia can be limited to one side of the body, which is referred to as hemiataxia. Several possible causes exist for these patterns of neurological dysfunction. Dystaxia is a mild degree of ataxia. Friedrich's ataxia has gait abnormality as the most commonly presented symptom.

Types

Cerebellar

The term cerebellar ataxia is used to indicate ataxia that is due to dysfunction of the cerebellum. The cerebellum is responsible for integrating a significant amount of neural information that is used to coordinate smoothly ongoing movements and to participate in motor planning. Although ataxia is not present with all cerebellar lesions, many conditions affecting the cerebellum do produce ataxia. People with cerebellar ataxia may have trouble regulating the force, range, direction, velocity and rhythm of muscle contractions. This results in a characteristic type of irregular, uncoordinated movement that can manifest itself in many possible ways, such as asthenia, asynergy, delayed reaction time, and dyschronometria. Individuals with cerebellar ataxia could also display instability of gait, difficulty with eye movements, dysarthria, dysphagia, hypotonia, dysmetria and dysdiadochokinesia. These deficits can vary depending on which cerebellar structures have been damaged, and whether the lesion is bilateral or unilateral.

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Well that is what we cry
Feelings we keep inside
And you are not in the right
And you've no reason to hide
It's that we must collide
Nothing can overwrite
And you are not on my side
And we will never arrive
Be quiet at times to learn
That's /Life's about to take a turn
And I am fixing to burn
From which I'll not return
A little bit of love
From somebody above
Life is addition in any way
There's no such time now as today, today
Saw you walking back from a nightmare
Won't change what you're to do, well I don't care
I grew up there and I wasn't scared
I am from there, I was born there
Forgive me if I cry
Look when you lifted the sky
Everybody emptied their slime
Those memories stole my side
And will you sit by my side,
If me not live past tonight?
Life isn't here and so streaming
What was the feeling to stream again, stream again?
I am becoming a voyeur
I am a small man, I told ya
I don't miss coming at all
Saw you walking back from a nightmare
Won't change what you're to do, well I don't care
I grew up there and I wasn't scared
I am from there, I was born there
Well that is what we cry
Feelings we keep inside
And you are not in the right
And you've no reason to hide
That's when we must collide
Nothing can overwrite
And you are not by my side
And we will not arrive
Saw you walking back from a nightmare
Won't change what you're to do, well I don't care
I grew up there and I wasn't scared

Latest News for: ataxia

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Lexeo Therapeutics Announces Positive Interim Phase 1/2 Data for LX2006 in Friedreich Ataxia Cardiomyopathy Supporting ...

Nasdaq Globe Newswire 07 Apr 2025

Lexeo Therapeutics Announces Positive Interim Phase 1/2 Data for LX2006 in Friedreich Ataxia Cardiomyopathy Supporting Advancement to Registrational Study ... .

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Lexeo Therapeutics Announces Positive Interim Phase 1/2 Data for LX2006 in Friedreich Ataxia

Enid News & Eagle 07 Apr 2025

Participants with abnormal left ventricular mass index (LVMI) at baseline achieved 25% mean reduction in LVMI by 12 months or sooner ... .

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Solaxa Announces Phase 3 Clinical Trial for Spinocerebellar Ataxia Type 27B

ACCESSWIRE 29 Mar 2025

Solaxa will serve as the regulatory sponsor of the trial and partner with leading ataxia centers of excellence ... There are currently no FDA approved therapies for SCA27B, a rare hereditary ataxia.

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See photos as Wicklow concert raises significant funds for Friedreich’s Ataxia research

Irish Independent 25 Mar 2025

... and their rare disease, Friedreich’s Ataxia.

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Living with Friedreich’s Ataxia: The loneliness of losing control

Canoe 25 Mar 2025

Eventually, they came to a formal and accurate diagnosis of Friedreich’s ataxia (FA), a rare progressive neurodegenerative disease that causes impaired muscle control due to nervous system damage ... Growing up with Friedreich’s ataxia.

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Latest News for: ataxia

Lexeo Therapeutics Announces Positive Interim Phase 1/2 Data for LX2006 in Friedreich Ataxia Cardiomyopathy Supporting ...

Lexeo Therapeutics Announces Positive Interim Phase 1/2 Data for LX2006 in Friedreich Ataxia

Solaxa Announces Phase 3 Clinical Trial for Spinocerebellar Ataxia Type 27B

See photos as Wicklow concert raises significant funds for Friedreich’s Ataxia research

Living with Friedreich’s Ataxia: The loneliness of losing control

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