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Arvinas Presents First-in-Human Data for Investigational Oral PROTAC ARV-102 Demonstrating

Hastings Tribune 04 Apr 2025
Data demonstrate that ARV-102 was well tolerated, orally bioavailable, and brain-penetrant; ARV-102 achieved central and peripheral LRRK2 reduction indicating substantial LRRK2 protein degradation in healthy volunteers – ... .
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Arvinas Presents First-in-Human Data for Investigational Oral PROTAC ARV-102 Demonstrating Blood-Brain Barrier Penetration, and Central ...

Nasdaq Globe Newswire 04 Apr 2025
Data demonstrate that ARV-102 was well tolerated, orally bioavailable, and brain-penetrant; ARV-102 achieved central and peripheral LRRK2 reduction indicating substantial LRRK2 protein degradation in healthy volunteers – ... .
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Arvinas Presents First-in-Human Data for Investigational Oral PROTAC ARV-102 Demonstrating Blood-Brain Barrier Penetration, and Central and Peripheral LRRK2 Degradation (Form 8-K) (Arvinas Inc)

Public Technologies 04 Apr 2025
) Arvinas Presents First-in-Human Data for Investigational Oral PROTAC ARV-102 Demonstrating Blood-Brain Barrier Penetration, and Central and Peripheral LRRK2 Degradation ... The SAD cohort evaluated ARV-102 doses ranging from 10 mg to 200 mg.
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