Artesunate
Artesunate (AS) is a medication used to treat malaria. It is water-soluble and may therefore be given by injection. It is a semi-synthetic derivative of artemisinin.
It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.
Medical uses
The World Health Organization recommends intramuscular or intravenous artesunate as the first line treatment for severe malaria. Artesunate was shown to prevent more deaths from severe malaria than quinine in two large multicentre randomized controlled trials from Africa and Asia. A subsequent systematic review of seven randomized controlled trials found this beneficial effect to be consistent across all trials.
For severe malaria during pregnancy, there is less certainty about the safety of artesunate during the first trimester but artesunate is recommended as first-line therapy during the second and third trimesters.
Artesunate is also used to treat less severe forms of malaria when it can be given orally, but should always be taken with a second antimalarial such as mefloquine or amodiaquine to avoid the development of resistance.
Podcasts:
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by Linkin Park
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by Emperor
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by Dutch Master
Iridescent
by: Linkin ParkYou were standing in the wake of devastation
You were waiting on the edge of the unknown
With the cataclysm raining down, insides crying save me now
You were there and possibly alone
Do you feel cold and lost in desperation
You build up hope, but failure's all you've known
Remember all the sadness and frustration
And let it go, let it go.
And in a burst of light that blinded every angel
As if the sky had blown the heavens into stars
You felt the gravity of tempered grace falling into empty space
No one there to catch you in their arms
Do you feel cold and lost in desperation
You build up hope, but failure's all you've known
Remember all the sadness and frustration
And let it go, let it go
Do you feel cold and lost in desperation
You build up hope, but failure's all you've known
Remember all the sadness and frustration
And let it go, let it go
Let it go
Let it go
Let it go
Let it go
Do you feel cold and lost in desperation
You build up hope, but failure's all you've known
Remember all the sadness and frustration