Arsenio is a Spanish and Italian male given name. It may refer to:
Arsenio is an American television sitcom that aired on ABC. The series starred Arsenio Hall and Vivica A. Fox. It aired from March 5 to April 23, 1997 with a total of 7 episodes produced.
Set in Atlanta, Georgia, Hall starred as Michael Atwood the host of a sports cable show on ASTV in Atlanta. Michael is also newly married man with his lawyer wife Vivian "Vicki" Deveaux Atwood (Vivica A. Fox). His co-host is Al (Kevin Dunn), who Michael sometimes asks for advice on his home life. Living with Michael and Vicki, is Vicki's younger brother Matthew (Alimi Ballard), a Harvard graduate who is not ready to take on the real world. Shawnee Smith also co-starred as Vicki's free-spirited old college friend Laura who is always encouraging Vicki to let loose.