The Arghun dynasty ruled the area between southern Afghanistan and the Sindh province of Pakistan from the late 15th century to the early 16th century. They claimed their descent and name from Ilkhanid-Mongol Arghun Khan, and were a dynasty of either Mongol,Turkic or Turco-Mongol ethnicity. The Arghuns can be divided into two branches: the Arghun branch of Dhu'l-Nun Beg Arghun that ruled until 1554, and the Tarkhan branch of Muhammad 'Isa Tarkhan that ruled until 1591.
In the late 15th century the Timurid sultan of Herat, Husayn Bayqarah, appointed Dhu'l-Nun Beg Arghun as governor of Kandahar. Dhu'l-Nun Beg soon began to ignore the authority of the central government in Herat and in around 1479 he began expanding in the direction of Baluchistan, taking over Pishin, Shal and Mustang. In 1485 his sons Shah Beg and Muhammad Mukim Khan also seized Sibi from the Samma dynasty of Sindh, although this gain was only temporary.
In 1497 Dhu'l-Nun Beg threw his support behind the revolt of Husayn Bayqarah's son Badi' al-Zaman against his father. Dhu'l-Nun Beg, who married off his daughter to Badi' al-Zaman, subsequently gained a prominent position in the latter's government when the Timurid succeeded Husayn Bayqarah in Herat in 1506. Unfortunately for them, the Uzbeks under Muhammad Shaybani invaded Khorasan shortly after Badi' al-Zaman's ascension. In 1507 Dhu'l-Nun Beg was killed in battle against the Uzbeks and succeeded by his sons Shah Beg and Mukim.
Arghun Khan aka Argon (Mongolian Cyrillic: Аргун хан) (c. 1258 – March 7, 1291) was the fourth ruler of the Mongol empire's Ilkhanate, from 1284 to 1291. He was the son of Abaqa Khan, and like his father, was a devout Buddhist (although pro-Christian). He was known for sending several embassies to Europe in an unsuccessful attempt to form a Franco-Mongol alliance against the Muslims in the Holy Land. It was also Arghun who requested a new bride from his great-uncle Kublai Khan. The mission to escort the young Kökötchin across Asia to Arghun was reportedly taken by Marco Polo. Arghun died before Kökötchin arrived, so she instead married Arghun's son, Ghazan.
Arghun was born to Abaqa Khan and his Christian princess wife, Haimash Khatun. Arghun himself had multiple wives, and his mother-in-law Bulughan Khatun raised Arghun's two sons Ghazan (whose birth mother was Qutlugh) and Öljeitü (whose birth mother was Uruk Khatun), both of whom later succeeded him and eventually converted to Islam. Arghun had Öljeitü baptized as a Christian at birth, and gave him the name Nikolya "Nicholas" after Pope Nicholas IV. According to the Dominican missionary Ricoldo of Montecroce, he was "a man given to the worst of villainy, but for all that a friend of the Christians".