Antigen

In immunology, an antigen is a molecule capable of inducing an immune response on the part of the host organism, though sometimes antigens can be part of the host itself. In other words, an antigen is any substance that causes an immune system to produce antibodies against it. Each antibody is specifically produced by the immune system to match an antigen after cells in the immune system come into contact with it; this allows a precise identification of the antigen and the initiation of a tailored response. The antibody is said to "match" the antigen in the sense that it can bind to it thanks to adaptations performed to a region of the antibody; because of this, many different antibodies can be produced, with specificity to bind many different antigens while sharing the same basic structure. In most cases, an antibody can only bind one specific antigen; in some instances, however, antibodies may bind more than one antigen.

In summary an antigen is a molecule that binds to Ag-specific receptors, but cannot necessarily induce an immune response in the body by itself. Antigens are usually peptides, polysaccharides or lipids. In general, molecules other than peptides (saccharides and lipids) qualify as antigens but not as immunogens since they cannot elicit an immune response on their own. Furthermore, for a peptide to induce an immune response (activation of T-cells by antigen-presenting cells) it must be a large enough size, since peptides too small will also not elicit an immune response. The term antigen originally described a structural molecule that binds specifically to an antibody. It expanded to refer to any molecule or a linear molecular fragment that can be recognized by highly variable antigen receptors (B-cell receptor or T-cell receptor) of the adaptive immune system.

Podcasts:

Antigen

ALBUMS

PLAYLIST TIME:

Antigen

by: Dynahead

Behind the mask of vanity
Lies the master of insanity
Encrypted look of who should be known
Old friends don't recognize
Their faces anymore
Behind the reflex of an heretic
Hides the devil of hypocrisy
Unspeakable words corrode his mouth
Faded embryo that should be dead
From the mirror comes the virtual twin
He hides my mysteries but reveal my sins
He, me, us in a splintered glass
Chromosomes of mutant me,
But not me
He moves like shadows envying me
And guess my attitudes before I begin
Rising enemy in a stolen corpse
The cocoon of a battle lost
From the mirror comes the virtual twin
He hides my mysteries but reveal my sins
He, me, in a splintered glass
Chromosomes of mutant me,
But not me
[Lead: Vilela]
From the mirror comes the virtual twin
He hides my mysteries but reveal my sins
He, me, us in a splintered glass
Chromosomes of mutant me,
But not me
[Lead: Mafra]




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