Fibroblast activation protein, alpha
Fibroblast activation protein alpha is a 170 kDa melanoma membrane-bound gelatinase, protein that in humans is encoded by the FAP gene.
Function
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.
FAP, also known as seprase, belongs to the clan SC proteases and is a member of the S9B prolyl oligopeptidase subfamily. Other members of the S9B subfamily are DPPIV, DPP8 and DPP9. FAP is most closely related to DPPIV and they share about 50% of their amino acids.
FAP is catalytically active as a 170kD dimer and has dipeptidase and gelatinase activity. Its gelatinase activity requires a glycine in P2 position.
FAP 1117
FAP 1117 was the predecessor of the latest FAP military truck version, FAP 1118. This is an all-terrain vehicle developed by VTI and scheduled for production by FAP factory in Priboj. It was not introduced in serial production, being only prototype, while it's lightly improved successor, FAP 1118 is in full serial production.
It is designed for transport of personnel, weapons and material of up to 4t gross weight, as well as for towing of artillery pieces and trailers. Equipped with all-wheel drive, locking of all differentials and powerful diesel engine, the vehicle is able to negotiate cross-country gradients of 60%. Central regulation of tire pressure assures high mobility over soft soil and its well thought out body geometry enables easy negotiating of natural and man-made obstacles such as trenches, railway embankments, escarps etc.
Technical characteristics
FAP 1118
The FAP 1118 is a series of 4x4 military trucks manufactured by Fabrika automobila Priboj (FAP), based on the Mercedes-Benz NG series. The FAP 1118 is intended to replace the TAM 110 series of military trucks in the Serbian Armed Forces.
Description
Its prototype was completed and tested and a trial lot is scheduled for realization by the end of this year. It is designed for transport of personnel, weapons and material of up to 4t gross weight, as well as for towing of artillery pieces and trailers. Equipped with all-wheel drive, locking of all differentials and powerful diesel engine, the vehicle is able to negotiate cross-country gradients of 60%. Central regulation of tire pressure assures high mobility over soft soil and its well thought out body geometry enables easy negotiating of natural and man-made obstacles such as trenches, railway embankments, escarps etc. There is a few different variants of truck as it is used for several different upgrade(Sanijet NBC, LRSVM Morava etc)
Andy
Andy may refer to:
Names
Places
Fictional characters
Music
Others
See also
Andy Dick
Andrew Roane "Andy" Dick (born December 21, 1965) is an American comedian, actor, musician, and television and film producer. Best known as a comic, he is also known for his eccentric and controversial behavior. His first regular television role was on the short-lived but influential Ben Stiller Show. In the mid-1990s, he had a long-running stint on NBC's NewsRadio and was a supporting character on Less than Perfect. He briefly had his own program, The Andy Dick Show on MTV. He is noted for his outlandish behavior from a number of Comedy Central Roasts. He landed in 7th place on the 16th season of Dancing with the Stars.
Early life
Dick was born in Charleston, South Carolina, on December 21, 1965, and he was adopted at birth by Allen and Sue Dick, and named Andrew Roane Dick. He was brought up Presbyterian, and as a child, he spent time living with his family in Connecticut, Pennsylvania, New York, and Yugoslavia before moving to Chicago in 1979. He attended Lassiter High School, which was being temporarily housed at George Walton Comprehensive High School in Cobb County, Georgia. Dick appeared in numerous theater productions during his high school years and was elected homecoming king his senior year in 1983. While in high school, Dick tended to use his name as a joke; and one day, he dressed in a homemade superhero costume and presented himself at school as "Super Dick". Dick graduated from Joliet West High School in 1984, and is a friend of actor Anthony Rapp, whom he had known since childhood. After graduating from high school, Dick joined Chicago's Second City, attended Columbia College Chicago, and took improv comedy classes at iO Theater.
Snoopy's siblings
In Charles M. Schulz's comic strip Peanuts, Snoopy was often stated to have seven siblings. Five appeared at various times in the strip: four brothers, Andy, Marbles, Olaf, and Spike; and one sister, Belle. The two others were never mentioned by name in the comic strip. According to the 1991 TV special Snoopy's Reunion, their names are Molly and Rover; however, their appearance is not considered canonical in the comic strip. In the June 6, 1959 comic strip, following the birth of Charlie Brown's sister Sally, Snoopy remarks that he has no brothers or sisters, and is an "only dog." However, in a March 18, 1971 strip, Snoopy writes in his autobiography: "I was born one bright Spring morning at the Daisy Hill Puppy Farm. I was one of eight puppies."
Their mother is called Missy, but has appeared only once in Peanuts, on July 26, 1996. A t-shirt that was sold for several years at Target and other stores shows Spike, Andy, Snoopy, Marbles and Olaf in a parody of the famous dogs playing poker print, despite much advertising copy which misidentified the characters.
