Alone (Why Must I Be Alone)

"Alone (Why Must I Be Alone)" is a popular song written by Morty Craft. Craft owned a record label, and produced the recording by the Shepherd Sisters on that label. The lyrics were written by Craft's wife, Selma.

While it was the only hit for The Shepherd Sisters (as The Sheps) in the United States (reaching #18 on the Billboard charts on November 11, 1957), in the United Kingdom it was one of a number of hits for Petula Clark (reaching #8 on the UK charts) before she became famous internationally. The Shepherd Sisters' version also charted in the UK, reaching #14, and another version, by The Southlanders, reached #17 on the UK chart.

A remake of the song by The Four Seasons charted in 1964, reaching its peak Billboard Hot 100 position at #28, on July 18. "Alone (Why Must I Be Alone" also went to #8 on the Canadian singles chart. It was the act's last hit single on Vee Jay Records, as The Four Seasons left the label at the beginning of 1964 in a royalty dispute. The Four Seasons recording of the song features a refrain that is whistled.

Love Amongst Ruin (album)

Love Amongst Ruin is the self-titled debut studio album by Love Amongst Ruin. It was released on September 13, 2010.

Background

Writing and recording

After departingPlacebo in October 2007, Steve Hewitt enlisted Lamb bassist Jon Thorne and his brother Nick Hewitt to begin writing and demoing new music at his home studio. Hewitt explained that he decided to write with Jon Thorne because he "wanted to play rock drums against somebody playing upright bass. And that’s what we did and the first thing we ever wrote was "Running"".Julian Cope collaborator Donald Ross Skinner was brought in to oversee and co-produce the recording sessions and the collective relocated to Moles Studio in Bath for three recording sessions with producer Paul Corkett over the summer of 2008. The sessions yielded ten songs, on which Steve performed drums and lead vocals. Mixing began in September and continued for six months before the album was mastered by Brian Gardner in April 2009.

"Bring Me Down (You Don't)" was to be included on the album, but legal trouble with publishers of the band Can resulted in the track being replaced with "Come On Say It". An acoustic version of the song was later released for free via SoundCloud in November 2011. "Come On Say It" featured then-band members Steve Hove, Laurie Ross and Keith York and was mixed ten weeks before the album's release. Other songs which were recorded, but didn't make the cut for the album, were cover versions of "Got To Give It Up" (Thin Lizzy) and "Rise" (Public Image Ltd), the latter being released for free via SoundCloud in July 2012.

Alone (1931 film)

Alone (Russian: Одна, meaning "Alone"), also known in English by the transliterated Russian title Odna, is a Soviet film released in 1931. It was written and directed by Leonid Trauberg and Grigori Kozintsev. It was originally planned as a silent film, but it was eventually released with a soundtrack comprising sound effects, some dialogue (recorded after the filming) and a full orchestral score by Dmitri Shostakovich. The film, about a young teacher sent to work in Siberia, is in a realist mode and addresses three political topics then current: education, technology, and the elimination of the kulaks.

Plot

The film tells the story of a newly graduated Leningrad teacher, Yelena Kuzmina (played by Yelena Alexandrovna Kuzmina). She goes furniture shopping with her fiance, Petya, and in a fantasy sequence she imagines teaching a class of neat, obedient city schoolchildren. Instead, she is assigned to work in the Altai mountains of Siberia. Reluctant to leave, she appeals to remain in the city. Although her request is granted (by a faceless Nadezhda Krupskaya, seen only from behind), she is eventually spurred by the government's condemnation of 'cowards' such as her to accept the post.

Addition

Addition (often signified by the plus symbol "+") is one of the four basic operations of arithmetic, with the others being subtraction, multiplication and division. The addition of two whole numbers is the total amount of those quantities combined. For example, in the picture on the right, there is a combination of three apples and two apples together; making a total of 5 apples. This observation is equivalent to the mathematical expression "3 + 2 = 5" i.e., "3 add 2 is equal to 5".

Besides counting fruits, addition can also represent combining other physical objects. Using systematic generalizations, addition can also be defined on more abstract quantities, such as integers, rational numbers, real numbers and complex numbers and other abstract objects such as vectors and matrices.

In arithmetic, rules for addition involving fractions and negative numbers have been devised amongst others. In algebra, addition is studied more abstractly.

Addition has several important properties. It is commutative, meaning that order does not matter, and it is associative, meaning that when one adds more than two numbers, the order in which addition is performed does not matter (see Summation). Repeated addition of 1 is the same as counting; addition of 0 does not change a number. Addition also obeys predictable rules concerning related operations such as subtraction and multiplication.

ADD1

Alpha-adducin is a protein that in humans is encoded by the ADD1 gene.

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described. Polymorphism in ADD1 is associated with hypertension.

References

Further reading

ADD3

Gamma-adducin is a protein that in humans is encoded by the ADD3 gene.

Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is composed of two distinct domains. The amino-terminal region is protease-resistant and globular in shape, while the carboxy-terminal region is protease-sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Alternatively spliced adducin gamma transcripts encoding different isoforms have been described. The functions of the different isoforms are not known.