Tuba
The tuba (UK /ˈtjuːbə/ or US /ˈtuːbə/;Italian pronunciation: [ˈtuːba]) is the largest and lowest-pitched musical instrument in the brass family. Sound is produced by vibrating or "buzzing" the lips into a large cupped mouthpiece. It first appeared in the mid 19th-century, making it one of the newer instruments in the modern orchestra and concert band. The tuba largely replaced the ophicleide.Tuba is Latin for 'trumpet'.
A person who plays the tuba is known as a tubaist or tubist. In the United Kingdom a person who plays the tuba in an orchestra is known simply as a tuba player; in a brass band or military band they are known as a bass player.
History
Prussian Patent No. 19 was granted to Wilhelm Friedrich Wieprecht and Johann Gottfried Moritz (1777–1840) on September 12, 1835 for a "basstuba" in F1. The original Wieprecht and Moritz instrument used five valves of the Berlinerpumpen type that were the forerunners of the modern piston valve. The first tenor tuba was invented in 1838 by Carl Wilhelm Moritz (1810–1855), son of Johann Gottfried Moritz.
Ṭūbā
Ṭūbā (Arabic: طُوبَىٰ ṭūbā, lit. "blessedness") is a tree that Muslims believe grows in Jannah, or Islamic heaven.
The tree is only mentioned once in the Koran but its attributes can be ascertained from various hadiths and other writings. Ṣaḥīḥ al-Bukhārī 4:474 notes that the tree spreads over a distance that can be covered in a hundred years and that the gowns of righteous dwellers of heaven are made from the fiber of its blossoms. A sage in Sohrevardi's The Red Intellect says that "any fruit you see in the world will be on that tree". The tree is sometimes described as being inverted and having its roots in the air. Mehmed Yazıcıoğlu (Yazıcızade, Yaziji-Oglu) wrote of the tree in "The Creation of Paradise" in his 1449 Book of Muhammad (Muhammediye):
That a tree which hangeth downward, high aloft its roots are there: Thus its radiance all the Heavens lighteth up from end to end, Flooding every tent and palace, every lane and every square. Such a tree the Tuba, that the Gracious One hath in its sap Hidden whatsoe'er there be of gifts and presents good and fair; Forth therefrom crowns, thrones, and jewels, yea, and steeds and coursers come, Golden leaves and clearest crystals, wines most pure beyond compare. For his sake there into being hath he called the Tuba-Tree, That from Ebu-Qasim's hand might every one receive his share.
Tuba (chief)
Tuba (also Tuvi or Toova; c. 1810–1887) was a Hopi leader in the late 19th century. Tuba was the headman of the small Hopi village of Moencopi, roughly fifty miles west of the main villages on the Hopi mesas. However, he apparently was an important person in the village of Oraibi as well. Eventually, Tuba joined The Church of Jesus Christ of Latter-day Saints (LDS Church) and later received his endowment in the St. George Temple. Tuba City, Arizona, was named in his honor.
Early life
Tuba was born in Oraibi, Arizona, as a member of the Short Corn Clan, or possibly the Pumpkin Clan. Hopi tradition does not record his birth name, but he told a Mormon missionary that said his Hopi name was "Woo Pah."
Tuba related to this same missionary that during the Mexican–American War (c. 1846), the Mexicans were in full retreat from the environs of the Hopi mesas. However, as they left they caused considerable trouble for the Hopis, and in fact one tried to steal a girl from Oraibi to take south with him. Apparently, Tuba's brother challenged the Mexican interloper to a kind of duel, and the pair fought with bowie knives in the village plaza. Tuba's brother was killed, but Tuba stepped in and killed the Mexican with a spear. This story seems of doubtful historical accuracy for several reasons. Among them, the story recounts that Tuba was eighteen years old when the duel occurred although he would have been in his mid-thirties at the time of the Mexican–American War.
Ahu
Ahu or AHU may refer to:
Polynesian religion
Places
People
Other uses
Easter Island
Easter Island (Rapa Nui: Rapa Nui, Spanish: Isla de Pascua) is a Chilean island in the southeastern Pacific Ocean, at the southeasternmost point of the Polynesian Triangle. Easter Island is famous for its 887 extant monumental statues, called moai, created by the early Rapa Nui people. In 1995, UNESCO named Easter Island a World Heritage Site, with much of the island protected within Rapa Nui National Park.
Polynesian people most likely settled on Easter Island sometime between 700 to 1100 CE, and created a thriving and industrious culture as evidenced by the island's numerous enormous stone moai and other artifacts. However, human activity, the introduction of the Polynesian rat and overpopulation led to gradual deforestation and extinction of natural resources which severely weakened the Rapa Nui civilization. By the time of European arrival in 1722, the island's population had dropped to 2,000–3,000 from an estimated high of approximately 15,000 just a century earlier. European diseases and Peruvian slave raiding in the 1860s further reduced the Rapa Nui population, to a low of only 111 inhabitants in 1877.
Sacubitril
Sacubitril (INN; developmental code name AHU-377) is an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure. It was approved under the FDA's priority review process for use in heart failure on July 7, 2015.
Mechanism of action
Sacubitril is a prodrug that is activated to sacubitrilat (LBQ657) by de-ethylation via esterases. Sacubitrilat inhibits the enzyme neprilysin, which is responsible for the degradation of atrial and brain natriuretic peptide, two blood pressure-lowering peptides that work mainly by reducing blood volume.
See also
References
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