Addiction
Addiction is a state characterized by compulsive engagement in rewarding stimuli, despite adverse consequences. It can be thought of as a disease or biological process leading to such behaviors. The two properties that characterize all addictive stimuli are that they are reinforcing (i.e., they increase the likelihood that a person will seek repeated exposure to them) and intrinsically rewarding (i.e., something perceived as being positive or desirable).
Addiction is a disorder of the brain's reward system which arises through transcriptional and epigenetic mechanisms and occurs over time from chronically high levels of exposure to an addictive stimulus (e.g., morphine, cocaine, sexual intercourse, gambling, etc.).ΔFosB, a gene transcription factor, is a critical component and common factor in the development of virtually all forms of behavioral and drug addictions; two decades of research into ΔFosB's role in addiction have demonstrated that addiction arises, and the associated compulsive behavior intensifies or attenuates, along with the genetic overexpression of ΔFosB in the D1-type medium spiny neurons of the nucleus accumbens; due to the causal relationship between ΔFosB expression and addictions, it is used preclinically as an addiction biomarker. ΔFosB expression in these neurons directly and positively regulates drug self-administration and reward sensitization through positive reinforcement, while decreasing sensitivity to aversion.
FLCL
FLCL (Japanese: フリクリ Hepburn: Furi Kuri, pronounced in English as Fooly Cooly) is an original video animation series written by Yōji Enokido, directed by Kazuya Tsurumaki and produced by the FLCL Production Committee, which consisted of Gainax, Production I.G, and King Records. FLCL follows Naota Nandaba, a twelve-year-old boy living in the fictional Japanese suburb of Mabase, and his interactions with Haruko Haruhara, who arrives in the quiet suburb, drawn by the industrial town houses and the Medical Mechanica building.
The English adaptation of the series was first licensed by Synch-Point which released the DVDs and soundtrack, but these went out of print in 2006. In January 2010, Funimation Entertainment announced that they would be re-releasing the series on DVD and releasing it for the first time on Blu-ray.
The series aired in America on Cartoon Network's Adult Swim in 2003 several times. It aired on the channel's Toonami block from October 26, 2013 to January 25, 2014. The series is also available via Hulu, iTunes, and on Funimation's website.
Podcasts:
Addict
ALBUMS
- Stones released: 1998
Alternative Video Results
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Addict
by: Static Radio NjGot a habit don't think you're gonna like it.
I couldn't say if I really tried to hide.
Soon you'll notice, soon you'll need to ask why.
Did it hurt to know I lied all about it?
I didn't really try to cover up the tracks.
What, you don't like me?
You don't need me?
Did you ever know me then?
Stupid habit.
I'm just an addict or I'm just alone.
Dancing rain falls down upon the sill,
we dream wet little dreams from all the violent films
and the little kids in us can't live without the high.
Let's stand up on the roof and kiss me one more time.
Stupid habit.
If we never sleep again then we got one more time
to smoke and watch the city lights collide.
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