Acura TLX

The Acura TLX is a mid-size luxury sedan manufactured by Acura, the luxury vehicle division of Honda, since 2014.

Design history

The Acura TLX was first shown as the "TLX Prototype", a sedan designed in Acura's Los Angeles Design Studio, as a replacement of the TL and TSX sedans. The production version was unveiled in April at the 2014 New York International Auto Show. Sales began in August, the TLX entered production during July at Marysville, Ohio, United States.

Production model

Two powertrain options are available. A 2.4-liter four-cylinder DOHC i-VTEC engine is available with direct injection mated to a dual-clutch transmission and Motion-Adaptive Electronic Power Steering, Precision All-Wheel Steer (P-AWS) through Integrated Dynamics System. The Honda designed dual clutch transmission is the first to use a torque converter, this is done to absorb transmission gear shift shock reducing NVH. Some customers experienced rough shifts and the TLX's transmission exhibits "unusual shifting behavior in its lower gears." "The TLX's transmission also drew criticism for a wide range of issues, including rough upshifts." The engine is rated at 206 hp with an EPA-estimated fuel economy of 24/35/28 mpg (city/highway/combined) compared to 22/31/26 from the previous TSX. Honda estimates it is 1.5 seconds faster from 0 to 60 mph, the 4-cylinder TLX will start at $31,890 or $360 more than the retiring TSX. Both the 4-cylinder TLX and 4-cylinder automatic TSX weigh the same.

TLX1

T-cell leukemia homeobox protein 1 is a protein that in humans is encoded by the TLX1 gene.

Interactions

TLX1 has been shown to interact with PPP1CC,PPP2CB and PPP2CA.

References

Further reading

TLX2

T-cell leukemia homeobox protein 2 is a protein that in humans is encoded by the TLX2 gene.

Interactions

TLX2 has been shown to interact with YWHAH.

References

Further reading

TLX3

T-cell leukemia homeobox protein 3 is a protein that in humans is encoded by the TLX3 gene.

RNX (HOX11L2, TLX3) belongs to a family of orphan homeobox genes that encode DNA-binding nuclear transcription factors. Members of the HOX11 gene family are characterized by a threonine-47 replacing cytosine in the highly conserved homeodomain (Dear et al., 1993).[supplied by OMIM]

References

Further reading