Act! (previously known as Sage ACT! 2010-2013) is a customer relationship management (CRM) software application which is used to keep track of client and prospect details in a single database that can be shared by multiple users. It integrates with Microsoft Word, Excel, Outlook, Google Contacts, Gmail and other popular applications in order to generate and track communications with the contacts maintained in ACT!. It is developed by Swiftpage and has a user base of over 2.8 million registered users.
According to 2013 CRM Switch survey, Act! is currently the 5th most popular CRM software application amongst US Businesses, and 4th most popular amongst companies with less than 100 employees. It was also ranked as the 2nd most popular CRM solution in Capterra's 2013 Top CRM Software Infographic.
Act! is currently available in English (US, UK and Australia), French, and German, and is sold through international resellers and ACT! Certified Consultants.
As of 2015, there are three editions of Act! -
Act! (Italian: Fare!, F!) is a centre-right political party in Italy, based in Veneto.
The party is led by Flavio Tosi, mayor of Verona and former leader of Liga Veneta–Lega Nord, who was ejected from it in the run-up of the 2015 Venetian regional election, due to his opposition to Matteo Salvini's political line.
Act! was immediately joined by three deputies (Matteo Bragantini, Roberto Caon, Emanuele Prataviera), three senators (Patrizia Bisinella, Raffaela Bellot, Emanuela Munerato) and four regional councilors in Veneto (three elected with the Tosi List for Veneto and one with Il Veneto del Fare). All of them were Tosi loyalists who followed him out of the League.
In July Michele Boldrin, leader of Act to Stop the Decline, sued Act! as the names of the two parties looked too similar.
In September a fourth deputy joined the party: Marco Marcolin, also from Liga Veneta–Lega Nord.
In October Act! became an occasional supporter of the centre-left government led by Matteo Renzi, whom Tosi held in high esteem, fueling rumors that the party might either enter in stable alliance with or join Renzi's Democratic Party.
An act is an instrument that records a fact or something that has been said, done, or agreed. Acts generally take the form of legal instruments of writing that have probative value and executory force. They are usually accepted as self-authenticating demonstrative evidence in court proceedings, though with the precarious status of notaries public and their acts under common law, this is not always so.
Common types of acts are legislative, judicial, and notarial acts.
Legislative acts (fully, acts of statute), or more commonly statutes, are the cornerstone of statutory and regulatory law. They may include in a monarchical system any royal edict, proclamation, or decree setting forth or establishing law as it affects all citizens. In parliamentary or congressional systems, acts passed by a legislature are known as acts of Parliament or acts of Congress.
A notarial act (or notarial instrument or notarial writing) is any written narration of facts (recitals) drawn up by a notary public or civil-law notary authenticated by his signature and official seal and detailing a procedure which has been transacted by or before him in his official capacity. A notarial act is the only lawful means of proving those facts of which it is the recognized record, whereas on other matters it is usually inadmissible, because, being beyond the powers entrusted to the notary by law, it is non-official. In most common-law countries, multiple-page acts are bound together using a sewn or knotted ribbon (referred to as silk), the ends of which are secured by a wafer impressed with the notary's seal. This is called annexing or annexure.
The Investment Company Act of 1940 is an act of Congress. It was passed as a United States Public Law (Pub.L. 76–768) on August 22, 1940, and is codified at 15 U.S.C. §§ 80a-1–80a-64. Along with the Securities Exchange Act of 1934 and Investment Advisers Act of 1940, and extensive rules issued by the Securities and Exchange Commission, it forms the backbone of United States financial regulation. It has been updated by the Dodd-Frank Act of 2010. Often known as the Company Act, the 1940 Act or simply the '40 Act, it is the primary source of regulation for mutual funds and closed-end funds, an investment industry now in the many trillions of dollars. In addition, the '40 Act impacts the operations of hedge funds, private equity funds and even holding companies.
Following the founding of the mutual fund in 1924, investors welcomed the innovation with open arms and invested in this new investment vehicle heavily. Five and a half years later, the Wall Street Crash of 1929 occurred in the stock market, followed shortly thereafter by the United States entry into the Great Depression. In response to this crisis, the United States Congress wrote into law the Securities Act of 1933 and the Securities Exchange Act of 1934 in order to regulate the securities industry in the interest of the public.
CRM may refer to:
CRM197 is a non-toxic mutant of diphtheria toxin, currently used as a carrier protein for polysaccharides and haptens to make them immunogenic.
CRM197 is a genetically detoxified form of diphtheria toxin. A single mutation at position 52, substituting glutamic acid for glycine, causes the ADP-ribosyltransferase activity of the native toxin to be lost. The structural basis for the lack of CRM197 toxicity has recently been elucidated. CRM197 is widely used as a carrier protein for conjugate vaccines. An advantage of CRM197 over toxoided proteins is that, because it is genetically detoxified, it retains its full complement of lysine amines for conjugation. There is also evidence suggesting that, compared with tetanus toxoid, there is less carrier-induced suppression of the immune response, especially when there are many individual polysaccharides linked to the same carrier protein. A summary of the uses and properties of CRM197 has been published. CRM197, like diphtheria toxin, is a single polypeptide chain of 535 amino acids (58.4 kD) consisting of two subunits (linked by disulfide bridges).
Exportin 1 (XPO1), also known as chromosomal maintenance 1 (CRM1), is an eukaryotic protein that mediates the nuclear export of proteins, rRNA, snRNA, and some mRNA.
Exportin 1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.
XPO1 has been shown to interact with: