Acacian schism
The Acacian schism between the Eastern and Western Christian Churches lasted thirty-five years, from 484–519. It resulted from a drift in the leaders of Eastern Christianity toward Miaphysitism, and Emperor Zeno's unsuccessful attempt to reconcile the parties with the Henotikon.
Chronology
In the events leading up to the Schism, Pope Felix III wrote two letters, one to Zeno and one to Acacius, Patriarch of Constantinople, reminding them of the need to defend the faith without compromise, as they had done previously.
When John Talaia, exiled from Alexandria, arrived in Rome and reported on what was happening in the East, Felix wrote two more letters, summoning Acacius to Rome to explain his conduct. The legates who brought these letters to Constantinople were imprisoned as soon as they landed and forced to receive Communion from Acacius as part of a Liturgy in which they heard Peter Mongus and other Miaphysites named in the diptychs. Felix, having heard of this from the Acoemeti monks in Constantinople, held a synod in 484 in which he denounced his legates and deposed and excommunicated Acacius.