JAG2
Protein jagged-2 is a protein that in humans is encoded by the JAG2 gene.
Function
The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene.
Interactions
JAG2 has been shown to interact with NOTCH2.
MicroRNA miR-1280 has been shown to inhibit JAG2 expression.
References
Further reading
JAG (TV series)
JAG (U.S. military acronym for Judge Advocate General) is an American legal drama television show with a distinct U.S. Navy theme, created by Donald P. Bellisario, and produced by Belisarius Productions in association with Paramount Network Television (now CBS Television Studios). The first season was co-produced with NBC Productions.
Originally perceived as a Top Gun meets A Few Good Men hybrid series, the pilot episode of JAG first aired on NBC on September 23, 1995, but the series was later canceled on May 22, 1996, after finishing 79th in the ratings, leaving one episode unaired. Rival network CBS picked up the series for a midseason replacement, beginning on January 3, 1997. For several seasons, JAG climbed in the ratings and was on the air for nine additional seasons. JAG furthermore spawned the hit series NCIS, which in turn spun off NCIS: Los Angeles and NCIS: New Orleans.
In total, 227 episodes were produced over 10 seasons. At the time of the original airing of its fifth season in the United States, JAG was seen in over 90 countries worldwide.JAG entered syndication early in 1999.
Circle
A circle is a simple shape in Euclidean geometry. It is the set of all points in a plane that are at a given distance from a given point, the centre; equivalently it is the curve traced out by a point that moves so that its distance from a given point is constant. The distance between any of the points and the centre is called the radius.
A circle is a simple closed curve which divides the plane into two regions: an interior and an exterior. In everyday use, the term "circle" may be used interchangeably to refer to either the boundary of the figure, or to the whole figure including its interior; in strict technical usage, the circle is only the boundary and the whole figure is called a disk.
A circle may also be defined as a special ellipse in which the two foci are coincident and the eccentricity is 0, or the two-dimensional shape enclosing the most area per unit perimeter squared, using calculus of variations.
Terminology
Circle (2014 film)
Circle (Turkish: Daire) is a 2014 film written and directed by director Atil Inac.
Plot
In the hard-boiled world, where will the soft-shelled end up? A cozy kind of extermination is on the stage and keeping a low profile. The decadence around us is nothing less than clandestine annihilation of the civil man. Yet it is carried out so well with a grinning face, it is officially sold as transition. Now that the tamed indulgent is striped off social justice, welfare, even denied the tender love of concentration camps and slavery plantations of past centuries. At least hand them a round of rope… They have high expectations from taking things in their own hands.
Circle is a peculiar story of an ordinary man caught between an untimely romance and brave new hostile world.
Characters
Awards
Circle (Eddie Izzard)
Circle is the name of a stand-up tour by the comedian Eddie Izzard in 2000.
It was released on VHS and DVD in the United Kingdom on 18 November 2002. The video includes Eddie performing a French version of his show with English subtitles.
The performance features many of Izzard's traditional themes, particularly religion (or "philosophies with some good ideas, and some fucking weird ones"). A discussion about Jesus' role in the three main Abrahamic faiths sees him "waiting offstage" in Judaism and playing on the same sporting team as Muhammad in Islam. This is counterpointed with a dialogue between a Crusader and his enemy in which both men are trying to kill the other "in the name of Jesus". He also mentions his impression that in Buddhism, Jesus is "Buddha's baby brother Benny".
The rigidity of religion is also lampooned, particularly as it relates to the Renaissance. Galileo's persecution by the Catholic Church is mentioned, although the man is eventually asked (in prison) "Galileo, Galileo, will you do the fandango?"
Unbroken
Unbroken may refer to:
Ships
- Unbroken, the story of a submarine, an autobiographical account of the submarine's patrols under the command of Alastair Mars
Literature, film, theatre and television
Music
Albums
Songs
Unbroken (D-Side album)
Unbroken is the third studio album by Irish boy band D-Side. The album was released on October 25, 2006 in Japan, and later released via the iTunes Store worldwide on March 3, 2008. The album peaked at number 58 on the Japanese album charts. Two singles were released from the album: the title track, "Unbroken", and "Let Me Be the One" (which serves as a promotional release only; no official music video was recorded for the song).
Background
"No One" was an unreleased track written by Bryan Adams. The album features writing contributions from a number of well-known songwriters, including two songs penned by Steve Mac and Wayne Hector ("Missing You" and "Then You Kissed Me"; the latter of which was an unreleased song by fellow boyband Westlife). The album's title track was also co-written by Phil Thornalley, famous for his work on Natalie Imbruglia's debut "Left of the Middle". The band co-wrote the mid-tempo ballad "Fly" with songwriter Kai McKenzie, who produced several tracks for the album. The original Japanese release includes four tracks omitted from the worldwide digital release, including the Mac-Hector "Then You Kissed Me".
