Protein atonal homolog 1 is a protein that in humans is encoded by the ATOH1 gene.
This protein belongs to the basic helix-loop-helix (BHLH) family of transcription factors. It activates E-box dependent transcription along with E47. ATOH1 is required for the formation of both neural and non-neural cell types. Using genetic deletion in mice, Atoh1 has been shown to be essential for formation of cerebellar granule neurons, inner ear hair cells, spinal cord interneurons, Merkel cells of the skin, and intestinal secretory cells (goblet, enteroendocrine, and Paneth cells). ATOH1 is a mammalian homolog of the Drosophila melanogaster gene atonal. ATOH1 is considered part of the Notch signaling pathway.
In 2009, ATOH1 was identified as a "cancer switch-off" gene.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
For a long time he's been lucky man
No difference if it's good or bad
The trigger's his - the orders others
No way to stop the final blow
The message: here ya go
The countdown's on a roll
War against the world
All systems deadly armed
Machine, man, all in one
They're all oblivious to the crime
Braindead hero
Braindead hero - out of the sun he comes
Braindead hero
Braindead hero - feel the blazing guns
Now we got to blow his circuitry
Drain the poison from his veins
Degenerate - corrupt his memories
Fire at will - just do or die
The message: here ya go
The countdown's on a roll
War against the world
All systems deadly armed
Machine, man, all in one
They're all oblivious to the crime
Braindead hero
Braindead hero -like a hammer from the sky
Braindead hero
Braindead hero - supersonic cry
You better stay just where you are
Consequences in the fire
Braindead hero
Braindead hero - out of the sun he comes
Braindead hero