ATN

ATN is the Sydney flagship television station of the Seven Network in Australia. The licence, issued to a company named Amalgamated Television Services, a subsidiary of Fairfax, was one of the first four licences (two in Sydney, two in Melbourne) to be issued for commercial television stations in Australia. It began broadcasting on 2 December 1956.

The station formed an affiliation with GTV-9 Melbourne in 1957, in order to share content. In 1963, Frank Packer ended up owning both GTV-9 and TCN-9, so as a result the stations switched their previous affiliations. ATN-7 and HSV-7 joined to create the Australian Television Network, which later became the Seven Network. ATN-7 is the home of the national level Seven News bulletins.

The studios and transmission tower

The station opened in 1956 with principal offices and studios located at Mobbs Lane, Epping (a suburb about 18 kilometres north west of Sydney). The initial black and white cameras and other equipment was supplied by the Marconi Company of England. Conversion to PAL colour occurred on 1 March 1975. Digital DVB-T commenced on 1 January 2001.

ATN1

Atrophin-1 is a protein that in humans is encoded by the ATN1 gene. It is expressed in nervous tissue.

Function

Dentatorubral pallidoluysian atrophy is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion of a trinucleotide repeat within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.

Clinical significance

Mutations in ATN1 are associated with a form of trinucleotide repeat disorder known as "dentatorubral-pallidoluysian atrophy" or "dentatorubropallidoluysian atrophy".

Interactions

ATN1 has been shown to interact with:

References

Further reading

External links

Bis-choline tetrathiomolybdate

Bis-choline tetrathiomolybdate, or WTX101, is a salt of tetrathiomolybdate (TTM, MoS₄²⁻) and choline currently under investigation as a therapy against Wilson's disease, a rare and potentially fatal disease in which the body cannot regulate copper. Wilson disease is an autosomal recessive genetic disorder that is manifested by serious hepatic, neurologic or psychiatric symptoms. The disease is fatal if left undiagnosed and untreated. It is estimated that approximately 1 individual in every 15,000 worldwide have Wilson's disease, corresponding to approximately 30,000 individuals in the European Union and approximately 20,000 in the United States.

Bis-choline tetrathiomolybdate has been evaluated in clinical trials in patients with various forms of cancer and has received orphan designation in the US and EU as a potential therapy against Wilson disease.

Bis-choline salt of tetrathiomolybdate is a de-coppering therapy in clinical development against Wilson disease under the code name WTX101 by Wilson Therapeutics AB. Wilson Therapeutics was founded by HealthCap in 2012.

Past

The past is a term used to indicate the totality of events which occurred before a given point in time. The past is contrasted with and defined by the present and the future. The concept of the past is derived from the linear fashion in which human observers experience time, and is accessed through memory and recollection. In addition, human beings have recorded the past since the advent of written language.

The past is the object of such fields as history, memory, flashback, archaeology, archaeoastronomy, chronology, geology, historical geology, historical linguistics, law, ontology, paleontology, paleobotany, paleoethnobotany, palaeogeography, paleoclimatology, and cosmology.

References

See also

Sub Sub

Sub Sub were an English dance act from Handforth, Cheshire composed of Jimi Goodwin and twin brothers Andy and Jez Williams.

The threesome met at school in 1985 and became regulars at The Haçienda while composing their own material together. They had an underground 12" single ("Space Face" in 1991) and moderate commercial success in the early 1990s on Rob Gretton's label Rob's Records, including the single "Ain't No Love (Ain't No Use)" (featuring guest vocalist Melanie Williams) which reached #3 on the UK Singles Chart. The trio's only full-length album Full Fathom Five was released in September 1994.

After a fire destroyed their recording studio on Blossom Street in the Ancoats area of Manchester on the Williams twins' birthday in 1996, they started anew as the more indie-oriented act Doves in 1998. An unreleased collection of tracks meant to be featured on the band's second full-length album was issued in 1998 as Delta Tapes.

Discography

Albums

Past (Aitken)

Past is a 1935 outdoor sculpture by Robert Ingersoll Aitken, located in front of the National Archives Building in Washington, D.C., in the United States. John Russell Pope served as the sculpture's architect and Edward H. Ratti served as its carver. The sculpture is made of Indiana limestone and measures approximately 20 x 8 x 12 feet, with a base approximately 12 x 12 x 15 feet.Past is a companion piece to Present, also located in front of the National Archives Building.

See also

References

External links

Media related to Past (sculpture) at Wikimedia Commons

Coordinates: 38°53′36″N 77°01′24″W / 38.89323°N 77.02320°W / 38.89323; -77.02320

Programming

Programming may refer to:

See also