ATN1
Atrophin-1 is a protein that in humans is encoded by the ATN1 gene. It is expressed in nervous tissue.
Function
Dentatorubral pallidoluysian atrophy is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion of a trinucleotide repeat within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.
Clinical significance
Mutations in ATN1 are associated with a form of trinucleotide repeat disorder known as "dentatorubral-pallidoluysian atrophy" or "dentatorubropallidoluysian atrophy".
Interactions
ATN1 has been shown to interact with:
References
Further reading
External links
Podcasts:
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by Edenian
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by Edenian
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by Edenian
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by Edenian
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by Edenian
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by Edenian
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by Edenian
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by Edenian
When I Gave Her My Eden
by: EdenianCome, follow me, behold my sight
Pure and full of my glory
All that I saw did me delight
Sin with me in my own story
So close my eyes
You’re real to me as sin I’ve done
My every breath you hold inhaled
No one can grab my memory…
Behold I rise, and now I know
I won the prize, your poison shed would be unshown
Chok’d up my path, no hid the face
You bring my Eden now
I was sent from high above
Just for you, in thy own dream
I will surround you by my love
Birds will sing deafen your scream
So close my eyes
You’re real to me as sin we done
My every breath you hold inhaled
No one can grab my memory…
Behold I rise, and now I know
I won the prize, your poison shed is now shown
Chok’d up my path, no hid the face
You fail my Eden now
Rise Eden to me so I gave her
My dreams will be untouched they were
Behold I rise, and now I know
I won the prize, your poison shed for me is shown
Chok’d up my path, no hid the face