Activating transcription factor 5, also known as ATF5, is a protein that, in humans, is encoded by the ATF5 gene.
First described by Nishizawa and Nagata, ATF5 has been classified as a member of the activating transcription factor (ATF)/cAMP response-element binding protein (CREB) family.
ATF5 transcripts and protein are expressed in a wide variety of tissues, in particular, high expression of transcripts in liver. It is also present in a variety of tumor cell types.
ATF5 expression is regulated at both the transcriptional and translational level.
ATF5 is expressed in VZ and SVZ during brain development.
The human ATF5 protein is made up of 282 amino acids.
ATF5 is a transcription factor that contains a bZip domain.
ATF5 has been shown to interact with DISC1 and TRIB3.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
She wiped the smile right off my face
And hid it away in a secret place
The night was dark and the ground was cold
I slipped myself into a pool
I saw the trees but not the wood
And floated in an icey flood
As cold began to freeze my heart
I heared a voice come through the dark
Bring up the coals
Light up the fire
Joy de viva
Joy de viva
Smile your shining smile on me
If you see her
Say I need her
Joy de viva
Joy de viva
Now sunburned men tell tales of me
Of how I sail the ocean deep
Upon the brow I shade my face
Searching for that sate of grace
Every night the moon appears
She shows me that I need not fear
The crashing rocks and siren wind
And I will find her in the end
Then I will run