APPL1
DCC-interacting protein 13-alpha is a protein that in humans is encoded by the APPL1 gene.
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.
Interactions
APPL1 has been shown to interact with Deleted in Colorectal Cancer and AKT2.
References
Further reading
Podcasts:
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by Lovin' Spoonful
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by Marisa Monte
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by Jalane
Apple Hill
by: Lovin' SpoonfulOne fine morning I got tired of hanging around
Took a footpath forty miles from town
and stopped to look around
Found a cabin with six dounble bunks
Just some flashlights and some lockers full of junk
Words of love scrawled on the wall
Lead me back through golden Falls
and happy days I spent at Apple Hill
I remember still the fun we had
at Apple Hill
Write your boyfriend's name upon the wall
We're gonna go swimmin' and we
won't wear clothes at all
Oh so many memeories
These few moments set them free
To spend some time with me
at Apple Hill
I remember still the fun we had
at Apple Hill
Happiness was summer days
and happiness was Apple Hill
Honeybees and balin' hay
Let your mind drift, if you will
back to happy days at Apple Hill