"Low" is the debut single by American rapper Flo Rida, featured on his debut studio album Mail on Sunday and also featured on the soundtrack to the 2008 film Step Up 2: The Streets. The song features fellow American rapper T-Pain and was co-written with T-Pain. There is also a remix in which the hook is sung by Flo Rida rather than T-Pain. An official remix was made which features Pitbull and T-Pain. With its catchy, up-tempo and club-oriented Southern hip hop rhythms, the song peaked at the summit of the U.S. Billboard Hot 100.
The song was a massive success worldwide and was the longest running number-one single of 2008 in the United States. With over 6 million digital downloads, it has been certified 7× Platinum by the RIAA, and was the most downloaded single of the 2000s decade, measured by paid digital downloads. The song was named 3rd on the Billboard Hot 100 Songs of the Decade. "Low" spent ten consecutive weeks on top of the Billboard Hot 100, the longest-running number-one single of 2008.
X-Dream are Marcus Christopher Maichel (born May 1968) and Jan Müller (born February 1970); they are also known as Rough and Rush. They are some of the cult hit producers of psychedelic trance music and hail from Hamburg, Germany.
The latest X-Dream album, We Interface, includes vocals from American singer Ariel Electron.
Muller was educated as a sound engineer. Maichel was a musician familiar with techno and reggae, and was already making electronic music in 1986. In 1989 the pair first met when Marcus was having problems with his PC and someone sent Jan to help fix it. That same year they teamed up to work on a session together. Their first work concentrated on a sound similar to techno with some hip hop elements which got some material released on Tunnel Records.
During the early 1990s they were first introduced to the trance scene in Hamburg and decided to switch their music to this genre. From 1993 they began releasing several singles on the Hamburg label Tunnel Records, as X-Dream and under many aliases, such as The Pollinator. Two albums followed on Tunnel Records, Trip To Trancesylvania and We Created Our Own Happiness, which were much closer to the original formula of psychedelic trance, although featuring the unmistakable "trippy" early X-Dream sound.
Radio is the fifth and latest studio album by Jamaican reggae and hip-hop artist Ky-Mani Marley, released on September 25, 2007. It topped the Billboard Reggae Charts at #1 in October 2007. The album features much more hip hop influences than his previous releases.
AMG-3 is an analgesic drug which is a cannabinoid agonist. It is a derivative of Δ8THC substituted with a dithiolane group on the 3-position side chain. AMG-3 is a potent agonist at both CB1 and CB2 receptors with a Ki of 0.32nM at CB1 and 0.52nM at CB2, and its particularly high binding affinity has led to it being used as a template for further structural development of novel cannabinoid drugs. It has sedative and analgesic effects, with analgesia lasting for up to 36 hours after administration.
AMG-36 is an analgesic drug which is a cannabinoid agonist. It is a derivative of Δ8THC substituted with a cyclopentane group on the 3-position side chain. AMG-36 is a potent agonist at both CB1 and CB2 with moderate selectivity for CB1, with a Ki of 0.4nM at CB1 vs 1.9nM at CB2.
AMG-1 is an analgesic drug which is a cannabinoid agonist. It is a derivative of Δ8THC with a rigidified and extended 3-position side chain. AMG-1 is a potent agonist at both CB1 and CB2 with moderate selectivity for CB1, with a Ki of 0.6nM at CB1 vs 3.1nM at CB2.