ALG12

Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase is an enzyme that in humans is encoded by the ALG12 gene.

This gene encodes a member of the glycosyltransferase 22 family. The encoded protein catalyzes the addition of the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation. Mutations in this gene have been associated with congenital disorder of glycosylation type Ig (CDG-Ig)characterized by abnormal N-glycosylation.

References

Further reading

External links

  • GeneReviews/NCBI/NIH/UW entry on Congenital Disorders of Glycosylation Overview

  • Podcasts:

    PLAYLIST TIME:

    Walk

    by: W.C.

    [Ice Cube]
    1, 2, 3, 4
    Get you a bitch up on the floor
    You gotta get up and get down (WALK!)
    You gotta get up and get down (WALK!)
    [WC]
    To the Weeeeeeest, MARCH
    Bang, crease the starch
    Uh oh, here we go again
    Off the chain, that Dub SC gang
    State yo name
    [Ice Cube]
    Ice Cube motherfucker
    [WC]
    What's your name
    [Mack 10]
    Mack 10 motherfucker
    [WC]
    Well bang on, swang on
    Cause on mine I'ma G on, Dub C let a scene on
    Get my green on, with my white sling on
    Weather my rag in, with my khakis cuffed and dragging
    Three wheels, make the heat squeal
    This Westcoast shit is the shit that we built
    Who wanna bust with or fuck with him, and confess
    Y'all can't fuck with it, I'm out the roof with it, bang loose with it
    Dub C, from that Dub SC
    Fo sho to make ya peeps slang off the cheese man
    [Chorus]
    Walk, walk
    Niggas let me see you walk
    Walk, walk
    Bitches let me see you walk - 2x
    To the Weeeeeeest, MARCH
    Calling all cars, niggas look hard
    Near park cars, after dark
    Get toe start
    [Ice Cube]
    Ice Cube motherfucker, I represent this
    Don't mistake the masked up for the apprentice
    All you bitch ass niggas are defenseless
    Like a Catholic priest, and bout ten kids
    It's sunday school, I run you fools
    You ain't gone do shit
    I got the flip shit, to plant
    Spit it like I'm gone spit it
    Niggas wanna get it, but they won't admit it
    I'm connected and committed
    All the way bided, while you bullshitted
    I'm on exhibit, like a pitbull off the chain
    Motherfuckers gone flip out, ropes get ripped out
    Niggas gone trip out, crip out, get a four-fifth out
    Get bout, with a brickhouse, with my dick out saying fuck ya
    My whole career, I kept it gangsta and hustla
    [Chorus]
    [Mack 10]
    It's for the ghetto and the gutter everytime I spit
    For niggas that walk off that funkadelic shit
    I just might go psycho, and grab the automatic
    And let one off for the gangbang addicts
    Cause I'm westside connected like a hand in the glove
    And I'm the gangsta rap nigga that the D-Boys love
    Hopped out braided and valetd in the front of the club
    I hit the do' niggas speak, I hit em up with a dub
    And even on the east coast, I rep Hoo Bangin
    Iced out, creased khakis with a red flag hanging
    Fin to bust a bitch to give head, that's eating the jaw
    And if I let my hair down, all the hoes all hoes
    Get ya hood, ya polo, ya tribe, ya ?
    And ain't no niggas in the game that can beat this group
    Mack 10 and Connect, is the hood I claim
    We do the damn thang, and it's off the chain
    To the Weeeeeeest, MARCH
    Calling all cars, niggas look hard
    Near park cars, after dark
    Get toe start - 2x
    [Chorus - 2x]




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