ALAS1

Delta-aminolevulinate synthase 1 also known as ALAS1 is a protein that in humans is encoded by the ALAS1 gene. ALAS1 is an aminolevulinic acid synthase.

Delta-aminolevulinate synthase catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2.

References

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


Loading... please wait...
This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/ALAS1

Podcasts:

Email this Page Play all in Full Screen Show More Related Videos
PLAYLIST TIME:

River Running

by: Alias Eye

Slowly moving onwards -
Perceive the light of day
Hazy in the distance -
No need for delay
A piercing ray of sunlight -
The moring will prevail
Horizons getting clearer -
The darkness lifts her veil
A myraid of colours -
A rainbow drop of dew
Scatters iron bridges -
Of thoughts I always knew
A turbulent upheaval -
The water froths and churns
As if the cool surroundings -
Is laughing as it burns
A river flowing to the sea
No way of knowing its destiny
Skipping over stones and telling stories
Of a life carried along
The water making up a song
Settling for the motions -
Of pathways preordained
All must travel onwards -
The riverbed maintained
Delight in our confinement -
Make haste and join the fray
The stone of life is rolling -
No time to halt and play
A river flowing to the sea
No way of knowing its destiny
Skipping over stones and telling stories
Of a life carried along
The water making up a song
A space opens before me -
A journey's at an end
Pain or true salvation -
What's waiting round the bend?
Mingling with the silence -
I hear a distant roar
The end I had imagined -
Is just another door
A river flowing to the sea
No way of knowing its destiny
Skipping over stones and telling stories
Of an end that never is




×
×
×
×