ABCC4
ATP-binding cassette sub-family C member 4 (ABCC4), also known as the multidrug resistance-associated protein 4 (MRP4) or multi-specific organic anion transporter B (MOAT-B), is a protein that in humans is encoded by the ABCC4 gene.
ABCC4 acts as a regulator of intracellular cyclic nucleotide levels and as a mediator of cAMP-dependent signal transduction to the nucleus. MRP4/ABCC4 also transports prostaglandins, for example PGE2, out of the cell where they can bind receptors.
MRP4/ABCC4 expression is dysregulated in several cancers and is also upregulated in peritoneal endometriosis.
Interactive pathway map
Click on genes, proteins and metabolites below to link to respective articles.
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Fluorouracil (5-FU) Activity edit
See also
References
Further reading
External links
Human Genome Organisation
The Human Genome Organisation (HUGO) is an organization involved in the Human Genome Project, a project about mapping the human genome. HUGO was established in 1989 as an international organization, primarily to foster collaboration between genome scientists around the world. The HUGO Gene Nomenclature Committee (HGNC), sometimes referred to as "HUGO", is one of HUGO's most active committees and aims to assign a unique gene name and symbol to each human gene.
History
HUGO was established in late April 1988 at the first meeting dedicated to genome mapping at Cold Spring Harbor. The idea of starting the organization stemmed from a South African biologist by the name of Sydney Brenner, who is known for his significant contributions to work on the genetic code and other areas of molecular biology, as well as winning the Nobel prize in Physiology of Medicine in 2002. A Founding Council was elected at the meeting that total 42 scientists from 17 different countries. HUGO is grounded in Geneva Switzerland, and later went on to elect an additional 178 members, bringing the total up to 220.
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Kill This Love
by: Epik HighENGLISH:
Somebody help me kill this!
Love. Kill this love. Kill this love. Love.
Somebody help me kill this!
Love. Kill this love. Kill this love. Love. Please don't die.
I should cut off the breath of my memories of you.
I've set fire to our recollections.
I hoped that my regrets will become a pile of ash
But they've only gotten hotter.
Even when I fill the bathtub with water
And dip myself in it to extinguish the fire
I hold my breath and soon, you come up again.
I hold on to the regrets that have come up.
I cover the eyes of memories that are watching me.
I roll up my hatred and look around.
It's a desert everywhere, where I want to find tears.
I should bury away my little affections.
My emotions are still soft.
The line that's been shaken because of its weakness.
I should draw it well and finish if off.
Save me.
Please save me.
Save me.
Somebody help me kill this!
Love. Kill this love. Kill this love. Love. Please don't die.
Somebody help me kill this!
Love, love. Love, love.
Kill, kill, kill, kill this love.
Love, love. Love, love.
Kill, kill, kill, kill this.
I can't kill, kill, kill this love.
No, no, no, no.
God help me kill, kill, kill, kill, kill, this love.
Kill this love.
Every rainy night, you come looking for me again.
The pieces of memories, buried deep in my heart, fly towards me like an arrow.
You used to be my dream, so why?
You become a nightmare every night again.
You push me off into despair, when I don't even have wings.
Please answer me that it's over now.
It didn't work. Since you left me, my heart had a hole. Gunshot.
Using ‘disinfection' as my excuse,
I only depend on alcohol and drink it up in one shot like poison spreading in my whole body.
These days, I black out every day.
My hungry lonelienss starves me.
My thirsty regrets suffocate me.
If you live, I'll die. Don't you know?
Save me.
Please save me.
Save me.
Somebody help me kill this!
Love. Kill this love. Kill this love. Love. Please don't die.
Somebody help me kill this!
Love, love. Love, love.
Kill, kill, kill, kill this love.
Love, love. Love, love.
Kill, kill, kill, kill this.
I can't kill, kill, kill this love.
No, no, no, no.
God help me kill, kill, kill, kill, kill, this love.
Kill this love.
If you open my eyes, my eyes will close.
Redrum, redrum, redrum.
If you breathe, my breath will stop.
Redrum, redrum, redrum.
Somebody help me kill this!
Somebody help me kill, kill, kill this love.
God help me kill, kill, kill, kill, kill, this love.
Goodbye dear love.
RIP.
RIP.
RIP.
Goodbye, goodbye, goodbye.
Good night.
ROMANIZED
Somebody help me kill this!
Love. Kill this love. Kill this love. Love.
Somebody help me kill this!
Love. Kill this love. Kill this love. Love.?.
Ne gieogui sum kkeunheoyaji.
Chueoge bul butyeobwatji.
Huhoega jaega doegil baraetjiman
Deo tteugeowojyeogatji.
Yokjoe mureul bada
Bul kkeugi wihae
Nunmulbada soge damado
Sumeul chama got dasi tteooreuneun neoya.
Tteooreun miryeoneul butjaba.
Nal boneun gieogui nun maga.
Nae jeungoreul geotgo dulleobwa.
Ontong nunmulman chatgopeun samak.
Janjeongeul mudeoyaji. Gamjeongi mulleo. Ajik.
Nayakhae heundeullin seon. Ijen jal geutgo kkeutnaeyaji.
Nal jom sallyeojwoyo.
Jebal jom sallyeojwoyo.
Nal jom sallyeojwoyo.
Love. Kill this love. Kill this love. Love.?.
Somebody help me kill this!
Love, love. Love, love.
Kill, kill, kill, kill this love.
Love, love. Love, love.
Kill, kill, kill, kill this.
I can't kill, kill, kill this love.
No, no, no, no.
God help me kill, kill, kill, kill, kill, this love.
Kill this love.
Bioneun bam mada neon. Nal chajaseo tto wa.
Gaseume mudeotdeon gieogui tomageun hwasallo narawa.
Nae kkumideon niga wae? Tto maeil angmongi dwae. Nalgaedo
Eomneun nal mireo. Jeolmangeuro.
Ijeneun kkeuchira daedaphaejwo.
Soyongeopdeorago. Nega nal tteonago nae maeumeun gumeongna. Gunshot.
Sodogeul pinggyero sureman gidaego onmome dokcheoreom one shot.
Yojeumeun maennal pilleumi kkeunkyeo.
Heogijin oeroumi nal gurmgyeo.
Mongmareun miryeoni mogeul jolla.
Nega salmyeon naega jugeo. Molla?
Nal jom sallyeojwoyo.
Jebal jom sallyeojwoyo.
Nal jom sallyeojwoyo.
Somebody help me kill this!
Love. Kill this love. Kill this love. Love.?.
Somebody help me kill this!
Love, love. Love, love.
Kill, kill, kill, kill this love.
Love, love. Love, love.
Kill, kill, kill, kill this.
I can't kill, kill, kill this love.
No, no, no, no.
God help me kill, kill, kill, kill, kill, this love.
Kill this love.
Nega nuneul tteumyeon nae nuni gamgyeo.
Redrum, redrum, redrum.
Nega sumeul swimyeon nae sumi makhyeo.
Redrum, redrum, redrum.
Somebody help me kill this!
Somebody help me kill, kill, kill this love.
God help me kill, kill, kill, kill, kill, this love.
Goodbye dear love.
Rip.
Rip.
Rip.
Goodbye, goodbye, goodbye.