AB-005 or [1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)-methanone is a designer drug offered by online vendors as a cannabimimetic agent. The structure and pharmacological activity of AB-005 was published in 2010, prior to its commercial availability in 2012, where it was reported to have high affinity for both CB1 (Ki = 5.5 nM) and CB2 receptors (Ki = 0.48 nM). AB-005 features groups found in other previously reported synthetic cannabinoids: the tetramethylcyclopropane group of UR-144 and XLR-11 as well as the (1-methyl-2-piperidinyl)methyl substituent of AM-1248 and AM-1220. No information regarding the in vivo activity of AB-005 has been published, and only anecdotal reports are known of its psychoactivity in humans.
Psychoactive products in New Zealand containing this drug have been given interim approval under recent psychoactive substances legislation.
To be loved is a thrilling sensation as thrilling as can be
Though it happens in every nation they greet if differently
Every mademoiselle with pasoolala, every Englishman talks to his pater
Every spittin' Venetian goes tra la la and the Irish say Mother McCree
But when I look at you and I thrill like I do there is only one thing I can say
Oh boy! oh boy! oh boy! oh boy! oh boy!
Oh boy what a joy, a joy, a joy, a joy, a joy
To know that you love me by heaven above me
I never expected to pick you off the vine
(The others will try and try and try and try and try
To give you the eye, the eye, the eye, the eye, the eye)
But when they approach you I'll keep them in line
By telling them oh boy oh boy oh boy you're mine
Certain characters hi-diddle-diddle when cupid comes along
Some mechanics shift gears in the middle and drummers kick the gong
Every cowboy I know hollers yipee-a-ay
Every clown in the circus goes oopla
Every sailor in port hollers anchors aweigh
And an Indian gives you a ugg!
But when you hold me tight like you're doing tonight
There's only one thing I can say
Oh boy! oh boy! oh boy! oh boy! oh boy!
Oh boy what a joy, a joy, a joy, a joy, a joy
To know that you love me by heaven above me
I never expected to pick you off the vine
(The others will try and try and try and try and try
To give you the eye , the eye, the eye, the eye, the eye)
But when they approach you I'll keep them in line
By telling them oh boy oh boy oh boy