The 5-HT1 receptors are a subfamily of 5-HT receptors that bind the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).[1] The 5-HT1 subfamily consists of five G protein-coupled receptors (GPCRs) that are coupled to Gi/Go and mediate inhibitory neurotransmission, including 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E, and 5-HT1F. There is no 5-HT1C receptor, as it was reclassified as the 5-HT2C receptor. For more information, please see the respective main articles of the individual subtypes:
Main article: 5-HT1A receptor
Main article: 5-HT1B receptor
Main article: 5-HT1D receptor
Main article: 5-HT1E receptor
Main article: 5-HT1F receptor
See also [link]
References [link]
- ^ Hoyer D, Clarke DE, Fozard JR, Hartig PR, Martin GR, Mylecharane EJ, Saxena PR, Humphrey PP (1994). "International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin)". Pharmacol. Rev. 46 (2): 157–203. PMID 7938165. https://pharmrev.aspetjournals.org/cgi/content/abstract/46/2/157.
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