2CB-Ind

Systematic (IUPAC) name
(5-bromo-4,7-dimethoxy-2,3-dihydro-1H-inden-1-yl)methanamine
Clinical data
Pregnancy cat.	?
Legal status	Uncontrolled
Routes	Oral
Identifiers
CAS number	912342-23-5 N
ATC code	None
PubChem	CID 16086368
ChemSpider	17245022 Y
ChEMBL	CHEMBL424890 Y
Chemical data
Formula	C12H16BrNO2
Mol. mass	286.164 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C12H16BrNO2/c1-15-10-5-9(13)12(16-2)8-4-3-7(6-14)11(8)10/h5,7H,3-4,6,14H2,1-2H3 Y Key:HCLPGYNQMVSQIM-UHFFFAOYSA-N Y
N (what is this?)  (verify)

2CB-Ind is a conformationally-restricted derivative of the phenethylamine hallucinogen 2C-B, discovered in 2006 by a team at Purdue University. It acts as a moderately potent and selective agonist for the 5-HT_2A and 5-HT_2C receptors, but unlike the corresponding benzocyclobutene derivative TCB-2 which is considerably more potent than the parent compound 2C-B, 2CB-Ind is several times weaker, with racemic 2CB-Ind having a K_i of 47nM at the human 5-HT_2A receptor, only slightly more potent than the mescaline analogue (R)-jimscaline.^[1][2]

See also [link]

• AMMI

References [link]

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