Nanofibrous meshes refer to the structures made of ultra-fine polymeric fibers. Because of nanome... more Nanofibrous meshes refer to the structures made of ultra-fine polymeric fibers. Because of nanometer measure size with an excessive strength/weight ratio, they are actual suitable as a nanosystem for delivering drug molecules. Drug molecules which mixed in nanofibers, can be released from the surrounding environment by means of various mechanisms in different manners (burst release, sustainable release and tunable release). Nanofibers can be used by way of release rate controlling strategies as proper delivery structures for drug molecules.The objective of this review is to highpoint the capacity of nanofibers as novel releasing substances for profens (Propionic acid derivative drugs including Carprofen; Naproxen; Fenoprofen; Flurbiprofen; Ibuprofen; Ketoprofen and Tiaprofenic acid). The profens are a class of nonselective, nonsteroidal anti-inflammatory drugs (NSAIDs). These drug molecules are derivatives of 2-phenylpropanoic acid. All contain a chiral center resulting in the formation of two enantiomers (R and S) of each profen. In this review, full information will be reported about the new progresses for release behaviors of profen molecules form the novel nanofibrous delivery systems. The drug releasing kinetics of profen molecules from nanofibers will be described briefly. The authors use more than 80 articles , books and thesis published in the case of nanofibrous profens delivery and releasing systems.
The usage of clinical devices in the cardiovascular treatment, hemodialyze system and other biome... more The usage of clinical devices in the cardiovascular treatment, hemodialyze system and other biomedical applications has improved recently. Direct contacts of biomaterials like poly(lactic acid) biopolymer with blood result in the activating of platelets, white blood cells , coagulation structure and complement cascades. Poly(lactic acid) is a sustainable, renewable, compostable, biobased, biodegradable, bioabsorbable , biocompatible polymer. This polymer has many applications in the synthesis of blood contacting mats like nanofibrous vascular scaffolds and hemodialyze nanosheets. Mechanical interruption of the blood vessel wall throughout grafting of cardiovascular devices starts local hemostatic replies. Improving the safety of the blood contacting nanostructure grafts is a main necessity. The controlling of the interactions of proteins and platelets to the surface of a blood contacting biomaterial is a significant factor. So, the assessments of these material's influences on blood are necessary. This article references more than 80 articles published in the last decade and reviews the latest hemocompatibility assays of poly(lactic acid) nanostructures used in the blood contacting field.
Nanofibrous meshes refer to the structures made of ultra-fine polymeric fibers. Because of nanome... more Nanofibrous meshes refer to the structures made of ultra-fine polymeric fibers. Because of nanometer measure size with an excessive strength/weight ratio, they are actual suitable as a nanosystem for delivering drug molecules. Drug molecules which mixed in nanofibers, can be released from the surrounding environment by means of various mechanisms in different manners (burst release, sustainable release and tunable release). Nanofibers can be used by way of release rate controlling strategies as proper delivery structures for drug molecules. The objective of this review is to highpoint the capacity of nanofibers as novel releasing substances for profens (Propionic acid derivative drugs including Carprofen; Naproxen; Fenoprofen; Flurbiprofen; Ibuprofen; Ketoprofen and Tiaprofenic acid). The profens are a class of nonselective, nonsteroidal anti-inflammatory drugs (NSAIDs). These drug molecules are derivatives of 2-phenylpropanoic acid. All contain a chiral center resulting in the formation of two enantiomers (R and S) of each profen. In this review, full information will be reported about the new progresses for release behaviors of profen molecules form the novel nanofibrous delivery systems. The drug releasing kinetics of profen molecules from nanofibers will be described briefly. The authors use more than 90 articles, books and thesis published in the case of nanofibrous profens delivery and releasing systems.
The skin is the largest organ of the body, with a total area of about 20 square feet. ... The epi... more The skin is the largest organ of the body, with a total area of about 20 square feet. ... The epidermis, the outermost layer of skin, provides a waterproof barrier and creates our skin tone.The human skin is the outer covering of the body and is the largest organ of the integumentary system. The skin has up to seven layers of ectodermal tissue and guards the underlying muscles, bones, ligaments and internal organ. WOUND IS an injury to living tissue caused by a cut, blow, or other impact, typically one in which the skin is cut or broken.
Novel wound dressings have practiced incessant and noteworthy variations as the earliest periods. The expansion begins with the usage of natural-materials to merely covering the wounds to the materials of the existing period that could be particularly manufactured to display numerous unexpected purposes. The modern bandage-materials constructed via bio-polymeric nano-fibers holding several active-compounds that are useful for the healing of wounds. With the correct selections of bio-polymers using for production of these nano-fibrous materials, they could improve the healing of wounds expressively compared with the conventional dressing materials, such as gauze. The novel wound dressings could be completed such that they have bio-active ingredients, for instance anti-microbial, anti-bacterial, and anti-inflammatory agents, which could be released to the wounds improving their healing.
This review offers an overview of various kinds of wounds, operational factors in wound healing and different forms of wound dressing materials with a superior highlighting to those manufactured of nanofibers.
Nanoparticles are used mainly for the transmission of the therapeutic molecules (like drugs, prot... more Nanoparticles are used mainly for the transmission of the therapeutic molecules (like drugs, proteins, or DNA) to the organ/ tissue of human body. Polymeric nanoparticles are mostly applied for therapeutic effectiveness in cancer therapy. The micro environment of tumor tissues in vessels can assist nanoparticles in achieving their anticipated accumulation. Poly (lactic acid) (PLA) is a novel green polymer with natural sources (like sweet potato and sugar cane). PLA is a linear aliphatic which has great sustainability, renewability and compostability. PLA has popper mechanical, thermal and barrier properties. This biomaterial is thermoplastic polyester with biocompatibility, non-toxicity and biodegradability. Various forms of PLA nanoparticles are synthetized for biomedical applications like cancer treatments and wound healing process. This review article introduces the various structures of polylactic acid nanoparticles used to deliver anticancer drugs. Furthermore, the investigational approaches that are considered for using PLA nanoparticles in treatment of different types of cancers will be reported briefly.
Nanofibrous meshes refer to the structures made of ultra-fine polymeric fibers. Because of nanome... more Nanofibrous meshes refer to the structures made of ultra-fine polymeric fibers. Because of nanometer measure size with an excessive strength/weight ratio, they are actual suitable as a nanosystem for delivering drug molecules. Drug molecules which mixed in nanofibers, can be released from the surrounding environment by means of various mechanisms in different manners (burst release, sustainable release and tunable release). Nanofibers can be used by way of release rate controlling strategies as proper delivery structures for drug molecules.The objective of this review is to highpoint the capacity of nanofibers as novel releasing substances for profens (Propionic acid derivative drugs including Carprofen; Naproxen; Fenoprofen; Flurbiprofen; Ibuprofen; Ketoprofen and Tiaprofenic acid). The profens are a class of nonselective, nonsteroidal anti-inflammatory drugs (NSAIDs). These drug molecules are derivatives of 2-phenylpropanoic acid. All contain a chiral center resulting in the formation of two enantiomers (R and S) of each profen. In this review, full information will be reported about the new progresses for release behaviors of profen molecules form the novel nanofibrous delivery systems. The drug releasing kinetics of profen molecules from nanofibers will be described briefly. The authors use more than 80 articles , books and thesis published in the case of nanofibrous profens delivery and releasing systems.
The usage of clinical devices in the cardiovascular treatment, hemodialyze system and other biome... more The usage of clinical devices in the cardiovascular treatment, hemodialyze system and other biomedical applications has improved recently. Direct contacts of biomaterials like poly(lactic acid) biopolymer with blood result in the activating of platelets, white blood cells , coagulation structure and complement cascades. Poly(lactic acid) is a sustainable, renewable, compostable, biobased, biodegradable, bioabsorbable , biocompatible polymer. This polymer has many applications in the synthesis of blood contacting mats like nanofibrous vascular scaffolds and hemodialyze nanosheets. Mechanical interruption of the blood vessel wall throughout grafting of cardiovascular devices starts local hemostatic replies. Improving the safety of the blood contacting nanostructure grafts is a main necessity. The controlling of the interactions of proteins and platelets to the surface of a blood contacting biomaterial is a significant factor. So, the assessments of these material's influences on blood are necessary. This article references more than 80 articles published in the last decade and reviews the latest hemocompatibility assays of poly(lactic acid) nanostructures used in the blood contacting field.
Nanofibrous meshes refer to the structures made of ultra-fine polymeric fibers. Because of nanome... more Nanofibrous meshes refer to the structures made of ultra-fine polymeric fibers. Because of nanometer measure size with an excessive strength/weight ratio, they are actual suitable as a nanosystem for delivering drug molecules. Drug molecules which mixed in nanofibers, can be released from the surrounding environment by means of various mechanisms in different manners (burst release, sustainable release and tunable release). Nanofibers can be used by way of release rate controlling strategies as proper delivery structures for drug molecules. The objective of this review is to highpoint the capacity of nanofibers as novel releasing substances for profens (Propionic acid derivative drugs including Carprofen; Naproxen; Fenoprofen; Flurbiprofen; Ibuprofen; Ketoprofen and Tiaprofenic acid). The profens are a class of nonselective, nonsteroidal anti-inflammatory drugs (NSAIDs). These drug molecules are derivatives of 2-phenylpropanoic acid. All contain a chiral center resulting in the formation of two enantiomers (R and S) of each profen. In this review, full information will be reported about the new progresses for release behaviors of profen molecules form the novel nanofibrous delivery systems. The drug releasing kinetics of profen molecules from nanofibers will be described briefly. The authors use more than 90 articles, books and thesis published in the case of nanofibrous profens delivery and releasing systems.
The skin is the largest organ of the body, with a total area of about 20 square feet. ... The epi... more The skin is the largest organ of the body, with a total area of about 20 square feet. ... The epidermis, the outermost layer of skin, provides a waterproof barrier and creates our skin tone.The human skin is the outer covering of the body and is the largest organ of the integumentary system. The skin has up to seven layers of ectodermal tissue and guards the underlying muscles, bones, ligaments and internal organ. WOUND IS an injury to living tissue caused by a cut, blow, or other impact, typically one in which the skin is cut or broken.
Novel wound dressings have practiced incessant and noteworthy variations as the earliest periods. The expansion begins with the usage of natural-materials to merely covering the wounds to the materials of the existing period that could be particularly manufactured to display numerous unexpected purposes. The modern bandage-materials constructed via bio-polymeric nano-fibers holding several active-compounds that are useful for the healing of wounds. With the correct selections of bio-polymers using for production of these nano-fibrous materials, they could improve the healing of wounds expressively compared with the conventional dressing materials, such as gauze. The novel wound dressings could be completed such that they have bio-active ingredients, for instance anti-microbial, anti-bacterial, and anti-inflammatory agents, which could be released to the wounds improving their healing.
This review offers an overview of various kinds of wounds, operational factors in wound healing and different forms of wound dressing materials with a superior highlighting to those manufactured of nanofibers.
Nanoparticles are used mainly for the transmission of the therapeutic molecules (like drugs, prot... more Nanoparticles are used mainly for the transmission of the therapeutic molecules (like drugs, proteins, or DNA) to the organ/ tissue of human body. Polymeric nanoparticles are mostly applied for therapeutic effectiveness in cancer therapy. The micro environment of tumor tissues in vessels can assist nanoparticles in achieving their anticipated accumulation. Poly (lactic acid) (PLA) is a novel green polymer with natural sources (like sweet potato and sugar cane). PLA is a linear aliphatic which has great sustainability, renewability and compostability. PLA has popper mechanical, thermal and barrier properties. This biomaterial is thermoplastic polyester with biocompatibility, non-toxicity and biodegradability. Various forms of PLA nanoparticles are synthetized for biomedical applications like cancer treatments and wound healing process. This review article introduces the various structures of polylactic acid nanoparticles used to deliver anticancer drugs. Furthermore, the investigational approaches that are considered for using PLA nanoparticles in treatment of different types of cancers will be reported briefly.
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Papers by TAHEREH ZAMANI
Novel wound dressings have practiced incessant and noteworthy variations as the earliest periods. The expansion begins with the usage of natural-materials to merely covering the wounds to the materials of the existing period that could be particularly manufactured to display numerous unexpected purposes. The modern bandage-materials constructed via bio-polymeric nano-fibers holding several active-compounds that are useful for the healing of wounds. With the correct selections of bio-polymers using for production of these nano-fibrous materials, they could improve the healing of wounds expressively compared with the conventional dressing materials, such as gauze. The novel wound dressings could be completed such that they have bio-active ingredients, for instance anti-microbial, anti-bacterial, and anti-inflammatory agents, which could be released to the wounds improving their healing.
This review offers an overview of various kinds of wounds, operational factors in wound healing and different forms of wound dressing materials with a superior highlighting to those manufactured of nanofibers.
Novel wound dressings have practiced incessant and noteworthy variations as the earliest periods. The expansion begins with the usage of natural-materials to merely covering the wounds to the materials of the existing period that could be particularly manufactured to display numerous unexpected purposes. The modern bandage-materials constructed via bio-polymeric nano-fibers holding several active-compounds that are useful for the healing of wounds. With the correct selections of bio-polymers using for production of these nano-fibrous materials, they could improve the healing of wounds expressively compared with the conventional dressing materials, such as gauze. The novel wound dressings could be completed such that they have bio-active ingredients, for instance anti-microbial, anti-bacterial, and anti-inflammatory agents, which could be released to the wounds improving their healing.
This review offers an overview of various kinds of wounds, operational factors in wound healing and different forms of wound dressing materials with a superior highlighting to those manufactured of nanofibers.