Эчтәлеккә күчү

OSM (ген)

Wikipedia — ирекле энциклопедия проектыннан ([http://tt.wikipedia.org.ttcysuttlart1999.aylandirow.tmf.org.ru/wiki/OSM (ген) latin yazuında])
OSM
Сурәт
Нинди таксонда бар H. sapiens[d][1]
Кодлаучы ген OSM[d][1]
Молекуляр функция cytokine activity[d][2][3][3][…], oncostatin-M receptor binding[d][4][5], growth factor activity[d][6], cytokine activity[d][7][8][8][…] һәм oncostatin-M receptor binding[d][9][6][8]
Күзәнәк компоненты күзәнәк тышындагы өлкә[d][8][8][8] һәм күзәнәк тышындагы мохит[d][7][8]
Биологик процесс oncostatin-M-mediated signaling pathway[d][5], positive regulation of peptidyl-serine phosphorylation[d][10], развитие многоклеточного организма[d][11], иммун җавап[d][8], позитивная регуляция пролиферации клеток[d][6], positive regulation of acute inflammatory response[d][6], regulation of growth[d][8], пролиферация[d][12], negative regulation of hormone secretion[d][13], positive regulation of cell division[d][8], positive regulation of MAPK cascade[d][10], негативная регуляция пролиферации клеток[d][11], положительная регуляция транскрипции РНК полимеразой II промотор[d][10], positive regulation of tyrosine phosphorylation of STAT protein[d][14], regulation of signaling receptor activity[d][8], positive regulation of peptidyl-tyrosine phosphorylation[d][10][6], cytokine-mediated signaling pathway[d][8], positive regulation of phosphatidylinositol 3-kinase signaling[d][15], positive regulation of inflammatory response[d][15], позитивная регуляция сигналов от протеинкиназы В[d][15], oncostatin-M-mediated signaling pathway[d][8][6] һәм regulation of hematopoietic stem cell differentiation[d][12]

OSM (ген) (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[16][17]

  1. 1,0 1,1 UniProt
  2. N Malik, Kallestad J. C., Gunderson N. L. et al. Molecular cloning, sequence analysis, and functional expression of a novel growth regulator, oncostatin M // Mol. Cell. Biol.ASM, 1989. — ISSN 0270-7306; 1098-5549; 1067-8824doi:10.1128/MCB.9.7.2847PMID:2779549
  3. 3,0 3,1 GOA
  4. Tanaka M, Hara T, NG C. et al. Reconstitution of the functional mouse oncostatin M (OSM) receptor: molecular cloning of the mouse OSM receptor beta subunit // BloodAmerican Society of Hematology, Elsevier BV, 1999. — 12 p. — ISSN 0006-4971; 1528-0020PMID:9920829
  5. 5,0 5,1 B Mosley, Imus C. D., D Friend et al. Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation // J. Biol. Chem. / L. M. GieraschBaltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1996. — ISSN 0021-9258; 1083-351X; 1067-8816doi:10.1074/JBC.271.51.32635PMID:8999038
  6. 6,0 6,1 6,2 6,3 6,4 6,5 B Mosley, Imus C. D., D Friend et al. Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation // J. Biol. Chem. / L. M. GieraschBaltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1996. — ISSN 0021-9258; 1083-351X; 1067-8816doi:10.1074/JBC.271.51.32635PMID:8999038
  7. 7,0 7,1 N Malik, Kallestad J. C., Gunderson N. L. et al. Molecular cloning, sequence analysis, and functional expression of a novel growth regulator, oncostatin M // Mol. Cell. Biol.ASM, 1989. — ISSN 0270-7306; 1098-5549; 1067-8824doi:10.1128/MCB.9.7.2847PMID:2779549
  8. 8,00 8,01 8,02 8,03 8,04 8,05 8,06 8,07 8,08 8,09 8,10 8,11 8,12 GOA
  9. Tanaka M, Hara T, NG C. et al. Reconstitution of the functional mouse oncostatin M (OSM) receptor: molecular cloning of the mouse OSM receptor beta subunit // BloodAmerican Society of Hematology, Elsevier BV, 1999. — 12 p. — ISSN 0006-4971; 1528-0020PMID:9920829
  10. 10,0 10,1 10,2 10,3 Yin T, YC Y. Mitogen-activated protein kinases and ribosomal S6 protein kinases are involved in signaling pathways shared by interleukin-11, interleukin-6, leukemia inhibitory factor, and oncostatin M in mouse 3T3-L1 cells // J. Biol. Chem. / L. M. GieraschBaltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1994. — ISSN 0021-9258; 1083-351X; 1067-8816PMID:7508917
  11. 11,0 11,1 Rose T. M., Bruce A. G. Oncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6 // Proc. Natl. Acad. Sci. U.S.A. / M. R. Berenbaum[Washington, etc.], USA: National Academy of Sciences [etc.], 1991. — ISSN 0027-8424; 1091-6490doi:10.1073/PNAS.88.19.8641PMID:1717982
  12. 12,0 12,1 Miles S. A., O. Martínez-Maza, A. Rezai et al. Oncostatin M as a potent mitogen for AIDS-Kaposi's sarcoma-derived cells // Science / H. ThorpNorthern America: AAAS, 1992. — ISSN 0036-8075; 1095-9203doi:10.1126/SCIENCE.1542793PMID:1542793
  13. M Yamaguchi, N Miki, M Ono et al. Inhibition of growth hormone-releasing factor production in mouse placenta by cytokines using gp130 as a signal transducer // Endocrinology / T. K. WoodruffLos Angeles, Calif: Endocrine Society, OUP, 1995. — ISSN 0013-7227; 1945-7170doi:10.1210/ENDO.136.3.7867561PMID:7867561
  14. Maminishkis A. CNTF mediates neurotrophic factor secretion and fluid absorption in human retinal pigment epithelium // PLOS ONE / PLOS ONE EditorsPLoS, 2011. — ISSN 1932-6203doi:10.1371/JOURNAL.PONE.0023148PMID:21912637
  15. 15,0 15,1 15,2 Kijlstra A. MicroRNA-20a-5p suppresses IL-17 production by targeting OSM and CCL1 in patients with Vogt-Koyanagi-Harada disease // Br. J. Ophthalmol.BMJ, 2017. — ISSN 0007-1161; 1468-2079doi:10.1136/BJOPHTHALMOL-2017-311079PMID:28972028
  16. HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланды. 18 сентябрь, 2017 тикшерелгән.
  17. UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.
  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)