Trimazosin
| |||
| (IUPAC) ime | |||
|---|---|---|---|
| (2-hidroksi-2-metilpropil) 4-(4-amino-6,7,8-trimetoksihinazolin-2-il)piperazin-1-karboksilat | |||
| Klinički podaci | |||
| Identifikatori | |||
| CAS broj | 53746-46-6 | ||
| ATC kod | C02CA03 | ||
| PubChem[1][2] | 37264 | ||
| UNII | 31L760807H 
| ||
| ChEMBL[3] | CHEMBL513301
| ||
| Hemijski podaci | |||
| Formula | C20H29N5O6 | ||
| Mol. masa | 435,47 g/mol | ||
| |||
| Farmakoinformacioni podaci | |||
| Trudnoća | ? | ||
| Pravni status | |||
Trimazosin je simpatomimetički lek. On je alfa blokator.[4]
Završni stupanj sinteze trimazosina je[5]
- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.
- ↑ van Kalken CK, van der Meulen J, Oe PL, Vriesendorp R, Donker AJ (1986). „Pharmacokinetics of trimazosin and its effects on blood pressure, renal function and proteinuria during short-term therapy of patients with impaired renal function and hypertension”. Eur. J. Clin. Pharmacol. 31 (1): 63–8. DOI:10.1007/BF00870988. PMID 3780829.
- ↑ Hess, H. J.; 1972, U.S. Patent 3,669,968
