Heptadekanska kiselina
| Heptadekanska kiselina | |||
|---|---|---|---|
| |||
| IUPAC ime |
| ||
| Drugi nazivi | Margarinska kiselina n-margarinska kiselina n-Heptadekanska kiselina | ||
| Identifikacija | |||
| CAS registarski broj | 506-12-7 
| ||
| ChemSpider[1] | 10033
| ||
| MeSH | |||
| ChEBI | 32365 | ||
| ChEMBL[2] | CHEMBL1172910
| ||
| Jmol-3D slike | Slika 1 | ||
| |||
| |||
| Svojstva | |||
| Molekulska formula | C17H34O2 | ||
| Molarna masa | 270.45 g/mol | ||
| Agregatno stanje | beli kristali | ||
| Gustina | 0.853 g/cm3 | ||
| Tačka topljenja |
61 °C | ||
| Tačka ključanja |
227 °C (100 mm Hg) | ||
| Rastvorljivost u vodi | nerastvorljiva | ||
| Srodna jedinjenja | |||
| Srodna višemasne kiseline | Palmitinska kiselina Stearinska kiselina | ||
| Сродна једињења | Heptadekanol Heptadekanal | ||
|
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| Infobox references | |||
Heptadekanska kiselina ili margarinska kiselina je zasićena masna kiselina.
Njena formula je CH3(CH2)15COOH. Javlja se u masti i mlečnoj masti preživara.[3][4][5][6] Soli i estri heptadekanske kiseline se zovu heptadekanoati.
| Osobina | Vrednost |
|---|---|
| Particioni koeficijent[7] (ALogP) | 6,8 |
| Rastvorljivost[8] (logS, log(mol/L)) | -7,2 |
| Polarna površina[9] (PSA, Å2) | 37,3 |
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.
- ↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.
- ↑ R. P. HANSEN, F. B. SHORLAND & N. JUNE COOKE (1957). „Occurrence in Butterfat of n-Heptadecanoic Acid (Margaric Acid)”. Nature 179 (98). DOI:10.1038/179098a0.
- ↑ Lide David R., ur. (2006). CRC Handbook of Chemistry and Physics (87th izd.). Boca Raton, FL: CRC Press. 0-8493-0487-3.
- ↑ Susan Budavari, ur. (2001). The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals (13th izd.). Merck Publishing. ISBN 0-911910-13-1.
- ↑ „Human Metabolome Database, HMDB02259”. Pristupljeno 8. 11. 2008.
- ↑ Ghose, A.K., Viswanadhan V.N., and Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A 102: 3762-3772. DOI:10.1021/jp980230o.
- ↑ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE. (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488-1493. DOI:10.1021/ci000392t. PMID 11749573.
- ↑ Ertl P., Rohde B., Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714-3717. DOI:10.1021/jm000942e. PMID 11020286.
- Clayden Jonathan, Nick Greeves, Stuart Warren, Peter Wothers (2001). Organic chemistry. Oxford, Oxfordshire: Oxford University Press. ISBN 0-19-850346-6.
- Smith, Michael B.; March, Jerry (2007). Advanced Organic Chemistry: Reactions, Mechanisms, and Structure (6th izd.). New York: Wiley-Interscience. ISBN 0-471-72091-7.
- Katritzky A.R., Pozharskii A.F. (2000). Handbook of Heterocyclic Chemistry. Academic Press. ISBN 0080429882.
