Fenetilin

Fenetilin
(IUPAC) ime
	(RS)-1,3-dimetil- 7-[2-(1-fenilpropan-2-ilamino)etil]purin- 2,6-dion
Klinički podaci
AHFS/Drugs.com	Internacionalno ime leka
Identifikatori
CAS broj	3736-08-1
ATC kod	N06BA10
PubChem	19527
DrugBank	DB01482
ChemSpider	18398
UNII	YZ0N7VL5R3
KEGG	D07944
Hemijski podaci
Formula	C18H23N5O2
Mol. masa	341,408 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C18H23N5O2/c1-13(11-14-7-5-4-6-8-14)19-9-10-23-12-20-16-15(23)17(24)22(3)18(25)21(16)2/h4-8,12-13,19H,9-11H2,1-3H3 ; Key: NMCHYWGKBADVMK-UHFFFAOYSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status	? (CA) ? (SAD)
Način primene	Oralno

Fenetilin je sintetički prolek koji se koristi kao psihostimulans. On je u prodaji pod imenom Kaptagon.

Farmakologija

Fenetilin se metaboliše u telu do amfetamina (24,5 % oralne doze) i teofilina (13,7 % oralne doze), koji su aktivni psihostimulansi.^[5] Fiziološko dejstvo fenetilina je stoga rezultat kombinacije tri leka.^[6]

Reference

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
↑ Ellison T, Levy L, Bolger JW, Okun R. The metabolic fate of 3H-fenethylline in man. European Journal of Pharmacology 13:123, 1970.
↑ Chemical characterization of counterfeit captagon tablets seized in Jordan. Alabdalla MA. Forensic Science International. 2005 Sep 10;152(2-3):185-8.

Spoljašnje veze

	Portal Medicina
	Portal Hemija

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[4] Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.

[5] Ellison T, Levy L, Bolger JW, Okun R. The metabolic fate of 3H-fenethylline in man. European Journal of Pharmacology 13:123, 1970.

[6] Chemical characterization of counterfeit captagon tablets seized in Jordan. Alabdalla MA. Forensic Science International. 2005 Sep 10;152(2-3):185-8.

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