D-aminokiselina oksidaza
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D-aminokiselina oksidaza | |||||||||
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3D strukctur DAAO iz kvasca (monomer) | |||||||||
Identifikatori | |||||||||
EC broj | 1.4.3.3 | ||||||||
CAS broj | 9000-88-8 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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D-aminokiselina oksidaza (EC 1.4.3.3, L-amino kiselina:O2 oksidoreduktaza) je enzim sa sistematskim imenom D-amino-kiselina:kiseonik oksidoreduktaza (deaminacija).[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- D-aminokiselina +H2O + O2 2-okso karboksilat + NH3 +H2O2
Ovaj enzim je flavoprotein (FAD). On ima široku specifičnost za D-aminokiseline. Takođe deluje na glicin.
- ↑ Dixon, M. and Kleppe, K. (1965). „D-Amino acid oxidase. I. Dissociation and recombination of the haloenzyme”. Biochim. Biophys. Acta 96: 357-367. PMID 14314378.
- ↑ Dixon, M. and Kleppe, K. (1965). „D-Amino acid oxidase. II. Specificity, competitive inhibition and reaction sequence”. Biochim. Biophys. Acta 96: 368-382.
- ↑ Dixon, M. and Kleppe, K. (1965). „D-Amino acid oxidase. III. Effect of pH”. Biochim. Biophys. Acta 96: 383-389. PMID 14314379.
- ↑ Massey, V., Palmer, G. and Bennett, R. (1961). „The purification and some properties of D-amino acid oxidase”. Biochim. Biophys. Acta 48: 1-9. PMID 13767909.
- ↑ Meister, A. and Wellner, D. (1963). „Flavoprotein amino acid oxidase”. u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 7 (2nd izd.). New York: Academic Press. str. 609-648.
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.