The design and operating data needed to define the fuel characteristics, vessel internal components, nuclear steam supply system components, and reactor operation characteristics for Cycles 1 and 2 of the Peach Bottom 2 reactor are presented. The purpose is to provide reference quality data for use in the qualification of reactor core analysis methods and to provide the basis for the assessment of the irradiation environment during Cycles 1 and 2. The design data includes fuel assembly description, core component arrangements, control rod descriptions, core loading patterns, reactor internals description, and major piping arrangements. Hydraulic characteristics of the assemblies and the inlet orifices are also provided. Operating data is compiled for 24 steady-state points during Cycle 1 and 13 during Cycle 2. Each state point includes core average exposure, thermal power, pressure, flux, inlet subcooling, control configuration and axial in-core detector readings.