Non-alcoholic fatty liver disease (NAFLD) has emerged as the most prevalent liver disease
in the world, yet there are still no approved pharmacological therapies to prevent or treat this …

Class I phosphoinositide 3-kinase (PI3K) generates phosphatidylinositol 3, 4, 5-
trisphosphate (PtdIns (3, 4, 5) P 3) at the plasma membrane in response to growth factors …

The COVID-19 pandemic continues to ravage the world, with the United States being highly
affected. A vaccine provides the best hope for a permanent solution to controlling the …

Coproduction of knowledge is believed to be an effective way to produce usable climate
science knowledge through a process of collaboration between scientists and decision …

Circulating levels of the gut microbe-derived metabolite trimethylamine-N-oxide (TMAO)
have recently been linked to cardiovascular disease (CVD) risk. Here, we performed …

Emerging evidence suggests that microbes resident in the human intestine represent a key
environmental factor contributing to obesity-associated disorders. Here, we demonstrate that …

Feral cats (Felis catus) have devastated wildlife globally. In Australia, feral cats are
implicated in most recent mammal extinctions and continue to threaten native species. Cat …

We describe the design and performance of an adaptive optics retinal imager that is
optimized for use during dynamic correction for eye movements. The system incorporates a …

Abstract Knowledge is widely considered a key ingredient for effective and sustainable
water governance. In the Colorado River basin, collaborative programs have been …

Purpose The strong dose-dependent association between anthracyclines and
cardiomyopathy is further exacerbated by the co-occurrence of cardiovascular risk factors …