Absorption, distribution, metabolism, excretion, and toxicity (ADMET) properties play key roles
in the discovery/development of drugs, pesticides, food additives, consumer products, and …

admetSAR was developed as a comprehensive source and free tool for the prediction of
chemical ADMET properties. Since its first release in 2012 containing 27 predictive models, …

MicroRNAs (miRNAs) are small non-coding RNAs (typically consisting of 18–25 nucleotides)
that negatively control expression of target genes at the post-transcriptional level. Owing to …

Metal nanoparticles (NPs) with size comparable to their electron mean free path possess
unusual properties and functionalities 1 , serving as model systems to explore quantum and …

GroEL and GroES form a chaperonin nano-cage for proteins up to ∼60 kDa to fold in isolation.
Here we explored the structural features of the chaperonin cage critical for rapid folding …

Drug-target interaction (DTI) is the basis of drug discovery and design. It is time consuming
and costly to determine DTI experimentally. Hence, it is necessary to develop computational …

Abstract Knowledge graph embedding has been an active research topic for knowledge base
completion, with progressive improvement from the initial TransE, TransH, DistMult et al to …

MicroRNAs (miRNAs) are noncoding RNAs with 18–26 nucleotides; they pair with target
mRNAs to regulate gene expression and produce significant changes in various physiological …

Aneuploidy, an incorrect chromosome number, is a hallmark of cancer. Compounds that cause
lethality in aneuploid, but not euploid, cells could therefore provide new cancer therapies. …

Selective Induction of LTP and LTD by Postsynaptic [Ca 2+ ] i Elevation. Long-term potentiation
(LTP) and long-term depression (LTD), two prominent forms of synaptic plasticity at …