Gastric cancer is the fourth most common cancer globally, and is the second most common
cause of death from cancer worldwide. About three-quarters of newly diagnosed cases in …

Background Nanoliposomal irinotecan showed activity in a phase 2 study in patients with
metastatic pancreatic ductal adenocarcinoma previously treated with gemcitabine-based …

Background Cancer stem cells (CSCs) are considered responsible for the recurrence and
chemoresistance of cancer. Dysregulated autophagy is highly prevalent in many types of …

The aim of this article is to provide a review of six patients with the various stages of obturator
hernia and a diagnostic and therapeutic strategy in suspected cases. Obturator hernia is …

Overexpression of cyclin D is associated with the molecular tumorigenesis of gastric cancer.
The purpose of the present study was to investigate the expression of cyclin D in human …

BACKGROUND The interactions between cancer stem cells (CSCs) and tumor‐associated
macrophages (TAMs) can promote tumor progression, maintain the CSCs population, and …

Pancreatic ductal adenocarcinoma (PDAC) tumours carry multiple gene mutations and
respond poorly to treatments. There is currently an unmet need for drug carriers that can deliver …

Background Ampullary cancer has the best prognosis in periampullary malignancy but
unpredicted early recurrence after resection is frequent. The current study tried to find the …

Although traditional chemotherapy kills a fraction of tumor cells, it also activates the stroma
and can promote the growth and survival of residual cancer cells to foster tumor recurrence …

Liver fibrosis is a risk factor for hepatoma. Activated hepatic stellate cells (HSCs) play a critical
role in progression of hepatoma. Resected hepatoma patients with high α-SMA+ HSCs …