Analysis of a chemical plant defense mechanism in grasses

…, C Stettner, S Grün, A Winklmair, W Eisenreich… - Science, 1997 - science.org
In the Gramineae, the cyclic hydroxamic acids 2,4-dihydroxy-1,4-benzoxazin-3-one (DIBOA)
and 2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA) form part of the defense …

Carbon metabolism of intracellular bacterial pathogens and possible links to virulence

W Eisenreich, T Dandekar, J Heesemann… - Nature Reviews …, 2010 - nature.com
New technologies such as high-throughput methods and 13 C-isotopologue-profiling analysis
are beginning to provide us with insight into the in vivo metabolism of microorganisms, …

The deoxyxylulose phosphate pathway of terpenoid biosynthesis in plants and microorganisms

W Eisenreich, M Schwarz, A Cartayrade, D Arigoni… - Chemistry & biology, 1998 - cell.com
Recent studies have uncovered the existence of an alternative, non-mevalonate pathway for
the formation of isopentenyl pyrophosphate and dimethylallyl pyrophosphate, the two …

High CO2 levels drive the TCA cycle backwards towards autotrophy

…, E Pettinato, TM Steiner, A Mall, S König, W Eisenreich… - Nature, 2021 - nature.com
It has recently been shown that in anaerobic microorganisms the tricarboxylic acid (TCA)
cycle, including the seemingly irreversible citrate synthase reaction, can be reversed and used …

Cytidine 5′-triphosphate-dependent biosynthesis of isoprenoids: YgbP protein of Escherichia coli catalyzes the formation of 4-diphosphocytidyl-2-C-methylerythritol

…, S Herz, K Kis, W Eisenreich… - Proceedings of the …, 1999 - National Acad Sciences
2-C-methylerythritol 4-phosphate has been established recently as an intermediate of the
deoxyxylulose phosphate pathway used for biosynthesis of terpenoids in plants and in many …

Deoxyxylulose phosphate pathway to terpenoids

W Eisenreich, F Rohdich, A Bacher - Trends in plant science, 2001 - cell.com
Recently, a mevalonate-independent pathway was discovered in bacteria and plants that
leads to the formation of isopentenyl diphosphate and dimethylallyl diphosphate, the two basic …

Studies on the biosynthesis of taxol: the taxane carbon skeleton is not of mevalonoid origin.

W Eisenreich, B Menhard, PJ Hylands… - Proceedings of the …, 1996 - National Acad Sciences
A cell culture of Taxus chinensis was established to produce the diterpene 2alpha,5alpha,10beta,14beta-tetra-acetoxy4
++ +(20),11-taxadiene (taxuyunnanine C) in 2.6% (dry weight) …

Metabolic host responses to infection by intracellular bacterial pathogens

W Eisenreich, J Heesemann, T Rudel… - Frontiers in cellular and …, 2013 - frontiersin.org
The interaction of bacterial pathogens with mammalian hosts leads to a variety of physiological
responses of the interacting partners aimed at an adaptation to the new situation. These …

The non-mevalonate pathway of isoprenoids: genes, enzymes and intermediates

F Rohdich, K Kis, A Bacher, W Eisenreich - Current opinion in chemical …, 2001 - Elsevier
Although the mevalonate pathway had been considered for a long time as the unique source
of biosynthetic isoprenoids, an alternative pathway has recently been discovered. The first …

A possible primordial peptide cycle

C Huber, W Eisenreich, S Hecht, G Wachtershauser - Science, 2003 - science.org
α-Amino acids can undergo peptide formation by activation with carbon monoxide (CO)
under hot aqueous conditions in the presence of freshly coprecipitated colloidal (Fe,Ni)S. We …