Polymer‐based mRNA delivery strategies for advanced therapies
W Yang, L Mixich, E Boonstra… - Advanced Healthcare …, 2023 - Wiley Online Library
Messenger RNA (mRNA)‐based therapies offer great promise for the treatment of a variety
of diseases. In 2020, two FDA approvals of mRNA‐based vaccines have elevated mRNA …
of diseases. In 2020, two FDA approvals of mRNA‐based vaccines have elevated mRNA …
Probing the impact of sulfur/selenium/carbon linkages on prodrug nanoassemblies for cancer therapy
…, M Guo, M Sun, H Yu, Q Chen, W Yang… - Nature …, 2019 - nature.com
Tumor cells are characterized as redox-heterogeneous intracellular microenvironment due
to the simultaneous overproduction of reactive oxygen species and glutathione. Rational …
to the simultaneous overproduction of reactive oxygen species and glutathione. Rational …
Boronic acid compounds as potential pharmaceutical agents
W Yang, X Gao, B Wang - Medicinal Research Reviews, 2003 - Wiley Online Library
Boronic acid compounds have been used, because of their unique structural features, for the
development of potent enzyme inhibitors, boron neutron capture agents for cancer therapy, …
development of potent enzyme inhibitors, boron neutron capture agents for cancer therapy, …
Electrocatalytic Synthesis of Essential Amino Acids from Nitric Oxide Using Atomically Dispersed Fe on N‐doped Carbon
…, S Wang, Y Zhang, W Yang, J Yang… - Angewandte Chemie …, 2023 - Wiley Online Library
How to transfer industrial exhaust gases of nitrogen oxides into high‐values product is
significantly important and challenging. Herein, we demonstrate an innovative method for artificial …
significantly important and challenging. Herein, we demonstrate an innovative method for artificial …
Disulfide bond-driven oxidation-and reduction-responsive prodrug nanoassemblies for cancer therapy
B Sun, C Luo, H Yu, X Zhang, Q Chen, W Yang… - Nano …, 2018 - ACS Publications
Disulfide bonds have been widely used to develop reduction-responsive drug-delivery
systems (DDS) for cancer therapy. We propose that disulfide bonds might be also used as an …
systems (DDS) for cancer therapy. We propose that disulfide bonds might be also used as an …
The crosstalk between epilepsy and dementia: A systematic review and meta-analysis
L Chen, W Yang, F Yang, Y Yu, T Xu, D Wang… - Epilepsy & Behavior, 2024 - Elsevier
Background Epilepsy and dementia are bidirectional. The purpose of this review was to
investigate the epidemiological characteristics of and to identify the risk factors for epilepsy in …
investigate the epidemiological characteristics of and to identify the risk factors for epilepsy in …
Anion Modulation of Ag‐Imidazole Cuboctahedral Cage Microenvironments for Efficient Electrocatalytic CO2 Reduction
How to achieve CO 2 electroreduction in high efficiency is a current challenge with the
mechanism not well understood yet. The metal‐organic cages with multiple metal sites, tunable …
mechanism not well understood yet. The metal‐organic cages with multiple metal sites, tunable …
Bioinspired nanoplatelets for chemo-photothermal therapy of breast cancer metastasis inhibition
Breast cancer is associated with high mortality due to tumor metastasis. The anti-metastasis
efficacy of photochemotherapy is strictly limited by poor targeting capability with respect to …
efficacy of photochemotherapy is strictly limited by poor targeting capability with respect to …
[HTML][HTML] A restricted role for TYK2 catalytic activity in human cytokine responses revealed by novel TYK2-selective inhibitors
…, J Smith, Y Lai, A Zhou, B Zhang, W Yang… - The Journal of …, 2013 - journals.aai.org
TYK2 is a JAK family protein tyrosine kinase activated in response to multiple cytokines,
including type I IFNs, IL-6, IL-10, IL-12, and IL-23. Extensive studies of mice that lack TYK2 …
including type I IFNs, IL-6, IL-10, IL-12, and IL-23. Extensive studies of mice that lack TYK2 …
The first fluorescent diboronic acid sensor specific for hepatocellular carcinoma cells expressing sialyl Lewis X
W Yang, H Fan, X Gao, S Gao, VVR Karnati, W Ni… - Chemistry & biology, 2004 - cell.com
Carbohydrate antigens with subterminal fucosylation have been implicated in the
development and progression of several cancers, including hepatocellular carcinoma (HCC). …
development and progression of several cancers, including hepatocellular carcinoma (HCC). …