Rabies vaccines have evolved from the first crude nerve tissue vaccines developed by Louis
Pasteur and his colleagues in 1885. Currently, safe and efficacious rabies vaccines for
humans and animals are produced in several cell culture systems with 10 vaccine regimens
recommended by WHO and/or ACIP for pre-exposure and post-exposure prophylaxis in
humans. Rabies vaccines are a critical component in the strategy to reduce the dog rabies,
the cause of 98% of all global human rabies deaths. However, eliminating rabies in the …