Multiple regulation of peptide YY secretion in the digestive tract

T Onaga, R Zabielski, S Kato - Peptides, 2002 - Elsevier
In the last two decades, multiple aspects of the peptide YY (PYY) secretion have been
investigated. Besides fat and fatty acids, many luminal nutrients in the distal intestine appear to …

Tachykinin: recent developments and novel roles in health and disease

T Onaga - Biomolecular concepts, 2014 - degruyter.com
Over 80 years has passed since the discovery of substance P (SP), and a variety of
peptides of the tachykinin (TK) family have been found and investigated. SP, neurokinin A (NKA), …

Role of neurotensin in the regulation of gastric motility in healthy conscious sheep

T Onaga, T Shimoda, T Ohishi, Y Yasui… - Small Ruminant …, 2019 - Elsevier
The goal of present study was to determine the effects of the intravenous (iv) administration
of neurotensin (NT) on the ovine forestomach and abomasal motility in conscious sheep. NT …

Chemical specificity of short-chain fatty acids in stimulating insulin and glucagon secretion in sheep

…, K Murata, H Maeda, T Onaga… - American Journal …, 1994 - journals.physiology.org
The chemical specificity and structural requirements of short-chain fatty acids (SCFAs) in
stimulating pancreatic endocrine responses was investigated in conscious sheep. Normal …

PACAP stimulates pancreatic exocrine secretion via the vagal cholinergic nerves in sheep

T Onaga, K Okamoto, Y Harada, H Mineo, S Kato - Regulatory peptides, 1997 - Elsevier
The present study evaluates the possible role of the vagus nerves in mediating the stimulatory
effect of PACAP-27, PACAP-38 and VIP on the exocrine pancreas, especially on enzyme …

Effect of L364 718 on interdigestive pancreatic exocrine secretion and gastroduodenal motility in conscious sheep

T Onaga, H Mineo, S Kato - Regulatory peptides, 1997 - Elsevier
The present study examined roles of endogenous cholecystokinin (CCK) and CCK-A
receptors in the regulation of pancreatic exocrine secretion and gastroduodenal motility in …

Pituitary adenylate cyclase-activating polypeptide (PACAP) induces duodenal phasic contractions via the vagal cholinergic nerves in sheep

T Onaga, Y Harada, K Okamoto - Regulatory peptides, 1998 - Elsevier
This study examined the effect of intravenous infusion of pituitary adenylate cyclase-activating
polypeptide (PACAP) on duodenal motility in sheep and the mechanism of the action of …

Role of peptide YY in regulation of duodenal motility during the interdigestive period in sheep

T Onaga, S Kubagawa, S Lee, H Mineo, S Kato… - Journal of Comparative …, 1997 - Springer
Temporal coordination between duodenal migrating myoelectric complexes (MMC) and
pancreatic exocrine secretion, and the effects of porcine peptide YY (PYY) on gastroduodenal …

Effect of pituitary adenylate cyclase-activating polypeptide on exocrine and endocrine secretion in the ovine pancreas

T Onaga, M Uchida, M Kimura, M Miyazaki… - … and Physiology Part C …, 1996 - Elsevier
The role of pituitary adenylate cyclase-activating polypeptide (PACAP) in the regulation of
exocrine and endocrine pancreas was investigated in conscious sheep. Intravenous infusions …

Localization and secretion of epidermal growth factor in the parotid gland and its intragastric kinetics in sheep

T Onaga, Y Shimizu, H Hayashi, M Tsuji, D Endoh… - Life sciences, 2006 - Elsevier
Ruminants secrete a large quantity of saliva that is rich in electrolytes; however, it remains
unclear whether their parotid saliva contains epidermal growth factor (EGF). The present study …